Chronic Cannabis Intoxication and Propofol-Induced Salivation: Causes and Considerations.

Allison Derise, Carey Ford, Nazar Hafiz, Sudha Pandit, Aditya Vyas, Samuel Igbinedion, James Morris, Paul Jordan, Qiang Cai, Jonathan Steven Alexander
{"title":"Chronic Cannabis Intoxication and Propofol-Induced Salivation: Causes and Considerations.","authors":"Allison Derise,&nbsp;Carey Ford,&nbsp;Nazar Hafiz,&nbsp;Sudha Pandit,&nbsp;Aditya Vyas,&nbsp;Samuel Igbinedion,&nbsp;James Morris,&nbsp;Paul Jordan,&nbsp;Qiang Cai,&nbsp;Jonathan Steven Alexander","doi":"10.3390/pathophysiology29020018","DOIUrl":null,"url":null,"abstract":"<p><p>Legalization/decriminalization of cannabis will increase the numbers of patients who have had recent exposure to recreational or medical cannabis. Currently, little has been reported about potential interactions between cannabis use and Propofol anesthesia e.g., for oropharyngeal procedures. We describe three cases of 'cannabis-induced hypersalivation after propofol' (CHAP) and present our institutions' experience with this unique pharmacological combination. Increased hypersalivation may complicate procedures and represent a procedural risk of suffocation. We evaluate possible pharmacological interactions that might underlie this phenomenon and consider management options going forward.</p>","PeriodicalId":520741,"journal":{"name":"Pathophysiology : the official journal of the International Society for Pathophysiology","volume":" ","pages":"223-232"},"PeriodicalIF":0.0000,"publicationDate":"2022-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229402/pdf/","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pathophysiology : the official journal of the International Society for Pathophysiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/pathophysiology29020018","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

Abstract

Legalization/decriminalization of cannabis will increase the numbers of patients who have had recent exposure to recreational or medical cannabis. Currently, little has been reported about potential interactions between cannabis use and Propofol anesthesia e.g., for oropharyngeal procedures. We describe three cases of 'cannabis-induced hypersalivation after propofol' (CHAP) and present our institutions' experience with this unique pharmacological combination. Increased hypersalivation may complicate procedures and represent a procedural risk of suffocation. We evaluate possible pharmacological interactions that might underlie this phenomenon and consider management options going forward.

Abstract Image

Abstract Image

Abstract Image

慢性大麻中毒和异丙酚诱导的唾液分泌:原因和考虑。
大麻合法化/除罪化将增加最近接触过娱乐性或医用大麻的患者人数。目前,关于大麻使用和异丙酚麻醉之间的潜在相互作用的报道很少,例如用于口咽手术。我们描述了三例“大麻诱导的异丙酚后唾液过多”(CHAP),并介绍了我们机构的经验,这种独特的药理组合。加重的过度通气可能使手术复杂化,并具有窒息的手术风险。我们评估可能的药物相互作用,可能是这种现象的基础,并考虑未来的管理选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信