R Shruthi, Ns Kedarnath, Ns Mamatha, Prashanth Rajaram, Dinesh Bhadrashetty
{"title":"Articaine for surgical removal of impacted third molar; a comparison with lignocaine.","authors":"R Shruthi, Ns Kedarnath, Ns Mamatha, Prashanth Rajaram, Dinesh Bhadrashetty","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>Articaine is an amide local anesthetic that differs from other agents of its group due to the presence of thiophene ring instead of a benzene ring. Some researchers claim that articaine is superior to lidocaine in its biologic profile. The aim of the study is to compare the efficacy of articaine with that of lidocaine which has proven efficacy.</p><p><strong>Materials and method: </strong>This study was done on 50 subjects; 25 of them received 4 % articaine HCl with 1:100000 epinephrine and the next 25 received 2% lignocaine HCl with 1:100000 epinephrine. Time of injection, onset of anesthesia, amount of anesthetic injected were recorded. Efficacy was determined using visual analog scale. The values were statistically analyzed.</p><p><strong>Results: </strong>The mean onset time of anesthesia in study group was 2.07 ± 0.22 and 2.18 ± 0.26 minutes in comparison group. A mean duration of 4.28 +0.78 hours was seen with articaine group and 3.51 + 0.45 hours with the lignocaine group. No statistical difference between the two groups with regard to pain experience.</p><p><strong>Conclusion: </strong>Articaine has similar efficacy as that of lignocaine with slightly longer duration and can be used as an alternative to lignocaine in third molar surgeries.</p><p><strong>Clinical significance: </strong>Increased availability of local anesthetics has improved interest in research about dental pain control. a quest for new methods of pain reduction is always justified. How to cite this article: R Shruthi, S N Kedarnath, S Mamatha N, Rajaram P, Dinesh B. Articaine For Surgical Removal of Impacted Third Molar; A Comparison With Lignocaine. J Int Oral Health 2013; 5(1):48-53.</p>","PeriodicalId":520673,"journal":{"name":"Journal of international oral health : JIOH","volume":" ","pages":"48-53"},"PeriodicalIF":0.5000,"publicationDate":"2013-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768079/pdf/jioh-05-01-048.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of international oral health : JIOH","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2013/2/26 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Aim: Articaine is an amide local anesthetic that differs from other agents of its group due to the presence of thiophene ring instead of a benzene ring. Some researchers claim that articaine is superior to lidocaine in its biologic profile. The aim of the study is to compare the efficacy of articaine with that of lidocaine which has proven efficacy.
Materials and method: This study was done on 50 subjects; 25 of them received 4 % articaine HCl with 1:100000 epinephrine and the next 25 received 2% lignocaine HCl with 1:100000 epinephrine. Time of injection, onset of anesthesia, amount of anesthetic injected were recorded. Efficacy was determined using visual analog scale. The values were statistically analyzed.
Results: The mean onset time of anesthesia in study group was 2.07 ± 0.22 and 2.18 ± 0.26 minutes in comparison group. A mean duration of 4.28 +0.78 hours was seen with articaine group and 3.51 + 0.45 hours with the lignocaine group. No statistical difference between the two groups with regard to pain experience.
Conclusion: Articaine has similar efficacy as that of lignocaine with slightly longer duration and can be used as an alternative to lignocaine in third molar surgeries.
Clinical significance: Increased availability of local anesthetics has improved interest in research about dental pain control. a quest for new methods of pain reduction is always justified. How to cite this article: R Shruthi, S N Kedarnath, S Mamatha N, Rajaram P, Dinesh B. Articaine For Surgical Removal of Impacted Third Molar; A Comparison With Lignocaine. J Int Oral Health 2013; 5(1):48-53.
目的:阿替卡因是一种酰胺类局部麻醉剂,与同类药物不同的是,阿替卡因中存在噻吩环而不是苯环。一些研究人员声称阿替卡因在生物学特性上优于利多卡因。本研究的目的是比较阿替卡因与已证实有效的利多卡因的疗效。材料与方法:本研究共50例受试者;其中25例接受4%盐酸阿替卡因加1:10万肾上腺素治疗,25例接受2%盐酸利多卡因加1:10万肾上腺素治疗。记录注射时间、麻醉起效、麻醉剂量。采用视觉模拟量表测定疗效。对结果进行统计学分析。结果:研究组麻醉起效时间平均为2.07±0.22 min,对照组麻醉起效时间平均为2.18±0.26 min。阿替卡因组的平均持续时间为4.28 +0.78小时,利多卡因组的平均持续时间为3.51 + 0.45小时。两组在疼痛体验方面无统计学差异。结论:阿替卡因与利多卡因疗效相近,持续时间稍长,可作为第三磨牙手术中利多卡因的替代用药。临床意义:局部麻醉药的使用增加了人们对牙痛控制研究的兴趣。寻求减轻疼痛的新方法总是合理的。R Shruthi, S N Kedarnath, S Mamatha N, Rajaram P, Dinesh B. artitine用于手术切除阻生第三磨牙;与利多卡因的比较。国际口腔卫生杂志;2013;5(1): 48-53。