Feasibility of using biomarkers in blood serum as markers of effect following exposure of the lungs to particulate matter air pollution.

Q2 Biochemistry, Genetics and Molecular Biology

Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews Pub Date : 2013-01-01 DOI:10.1080/10590501.2013.763575

Timothy Elvidge, Ian P Matthews, Clive Gregory, Bastiaan Hoogendoorn

引用次数: 19

Abstract

Particulate matter (PM) air pollution has significant cardiopulmonary health effects. Serum biomarkers may elucidate the disease mechanisms involved and provide a means for biomonitoring exposed populations, thereby enabling accurate policy decisions on air quality standards to be made. For this review, research investigating association of blood serum biomarkers and exposure to PM was identified, finding 26 different biomarkers that were significantly associated with exposure. Recent evidence links different effects to different components of PM. Future research on biomarkers of effect will need to address exposure by all PM size fractions.

查看原文本刊更多论文

使用血清中的生物标记物作为肺部暴露于颗粒物空气污染后影响的标记物的可行性。

大气颗粒物污染对心肺健康有显著影响。血清生物标志物可以阐明所涉及的疾病机制，并提供一种对暴露人群进行生物监测的手段，从而能够就空气质量标准作出准确的政策决定。在本综述中，研究人员确定了血清生物标志物与PM暴露之间的关系，发现26种不同的生物标志物与暴露显著相关。最近的证据表明，不同的影响与PM的不同成分有关。未来对生物标志物影响的研究将需要解决所有PM大小组分的暴露问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews 环境科学-毒理学

CiteScore

6.20

自引率

0.00%

发文量

审稿时长

>24 weeks

期刊介绍： Journal of Environmental Science and Health, Part C: Environmental Carcinogenesis and Ecotoxicology Reviews aims at rapid publication of reviews on important subjects in various areas of environmental toxicology, health and carcinogenesis. Among the subjects covered are risk assessments of chemicals including nanomaterials and physical agents of environmental significance, harmful organisms found in the environment and toxic agents they produce, and food and drugs as environmental factors. It includes basic research, methodology, host susceptibility, mechanistic studies, theoretical modeling, environmental and geotechnical engineering, and environmental protection. Submission to this journal is primarily on an invitational basis. All submissions should be made through the Editorial Manager site, and are subject to peer review by independent, anonymous expert referees. Please review the instructions for authors for manuscript submission guidance.