Hepatitis viruses in heamodialysis patients: an added insult to injury?

Hepatitis research and treatment Pub Date : 2013-01-01 Epub Date: 2013-03-06 DOI:10.1155/2013/860514
Kranthi Kosaraju, Sameer Singh Faujdar, Aashima Singh, Ravindra Prabhu
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引用次数: 22

Abstract

Hepatitis B (HBV) and hepatitis C (HCV) viruses are the most important causes of chronic liver disease in patients with end stage renal disease on hemodialysis. The prevalence of hepatitis infection among hemodialysis patients is high and varies between countries and between dialysis units within a single country. This case-control study was undertaken to estimate the occurrence of HBV and HCV infections in patients undergoing hemodialysis in our tertiary care center. All patients receving hemodialysis at our centre with HCV or HBV infection were included in the study. The total number of patients admitted for hemodialysis during the study period was 1710. Among these, 26 patients were positive for HBV, 19 were positive for HCV, and 2 were positive for both HCV and HBV. Mean age of the infected cases in our study was 48.63 years. Mean duration of dialysis for infected cases was 4.8 years while that of the noninfected controls was 3.18 years. The mean dialysis interval was twice a week. Interventions to reduce the occurrence of these infections are of utmost need to reduce the risk of long-term complications among hemodialysis patients.

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血透患者的肝炎病毒:对损伤的又一次侮辱?
乙型肝炎(HBV)和丙型肝炎(HCV)病毒是终末期肾脏疾病血液透析患者慢性肝病的最重要原因。血液透析患者中肝炎感染的流行率很高,并且在不同国家之间以及一个国家内不同的透析单位之间有所不同。本病例对照研究旨在估计在我们三级保健中心接受血液透析的患者中HBV和HCV感染的发生率。所有在我们中心接受血液透析的HCV或HBV感染患者都被纳入研究。在研究期间接受血液透析治疗的患者总数为1710例。其中HBV阳性26例,HCV阳性19例,HCV和HBV均阳性2例。本组感染病例平均年龄48.63岁。感染病例的平均透析时间为4.8年,而未感染对照组的平均透析时间为3.18年。平均透析间隔为每周两次。减少这些感染发生的干预措施对于降低血液透析患者长期并发症的风险至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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