The role of fine-needle aspiration cytology in the diagnosis of Basal cell carcinoma.

ISRN Dermatology Pub Date : 2012-01-01 Epub Date: 2012-03-26 DOI:10.5402/2012/132196
Masoom Kassi, Pashtoon Murtaza Kasi, Abaseen Khan Afghan, Shah Mohammad Marri, Mahwash Kassi, Iqbal Tareen
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引用次数: 9

Abstract

Background/Aims. Basal cell carcinoma (BCC) is the most common malignant tumor of the skin in humans. The diagnosis of BCC is made clinically, which can then be confirmed microscopically. Biopsy or surgical excision of the lesion provides the specimen for histopathological examination, which is the mainstay for diagnosis. Fine-needle aspiration cytology (FNAC) on the other hand is an even simpler procedure, which can provide accurate diagnosis to confirm or exclude the malignancy. Methods. Here, we present our experience on the role of FNAC in diagnosing BCC. We were able to recruit 37 patients, of which 35 had BCC. Both FNAC and biopsy were obtained and then interpreted independently of one another. Results. Cytology correlated with histopathology in all cases except for 2 in which the yield was deemed inadequate. The sensitivity and specificity of fine-needle aspiration cytology for basal cell carcinoma were 94.3% and 100%, respectively. Conclusions. We, therefore, recommend this technique for the initial evaluation of a patient with suspected BCC or in cases of recurrence. The technique is cheap, quick, less invasive, and highly accurate for the diagnosis of BCC. The limitation of the technique is low yield in some of the cases.

细针穿刺细胞学在基底细胞癌诊断中的作用。
背景/目的。基底细胞癌(BCC)是人类最常见的皮肤恶性肿瘤。BCC的诊断是临床做出的,然后可以在显微镜下确诊。活检或手术切除病变为组织病理学检查提供标本,这是诊断的主要依据。另一方面,细针穿刺细胞学(FNAC)是一个更简单的程序,它可以提供准确的诊断,以确认或排除恶性肿瘤。方法。在此,我们就FNAC在诊断BCC中的作用提出我们的经验。我们招募了37名患者,其中35名患有基底细胞癌。获得FNAC和活检,然后相互独立地进行解释。结果。细胞学与组织病理学在所有情况下相关,除了2,其中产量被认为不足。细针穿刺细胞学检查对基底细胞癌的敏感性为94.3%,特异性为100%。结论。因此,我们推荐该技术用于疑似BCC患者或复发病例的初步评估。该技术便宜、快速、侵入性小,对BCC的诊断高度准确。该技术的局限性是在某些情况下产量低。
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