Biodegradable Magnesium Alloys: A Review of Material Development and Applications.

Abstract

Magnesium based alloys possess a natural ability to biodegrade due to corrosion when placed within aqueous substances, which is promising for cardiovascular and orthopedic medical device applications. These materials can serve as a temporary scaffold when placed in vivo, which is desirable for treatments when temporary supportive structures are required to assist in the wound healing process. The nature of these materials to degrade is attributed to the high oxidative corrosion rates of magnesium. In this review, a summary is presented for magnesium material development, biocorrosion characteristics, as well as a biological translation for these results.