F-FDG PET/CT as a potential valuable adjunct to MRI in characterising the Brodie's abscess.

F Fathinul, Aj Nordin
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引用次数: 7

Abstract

Chronic osteomyelitis (Brodie's abscess) is essentially a problem of diagnosis, and there may be considerable difficulty in distinguishing it from other benign and malignant bone lesions. Early diagnosis of Brodie's abscess is deemed important as the disease has a good curative potential following an appropriate antibiotic treatment. Of late, PET/CT using (18)F-FDG is taking a centre stage in the imaging of bone infection though documentation on its role in characterising the feature of Brodie's abscess is exceedingly scarce. On the other hand, it is well known that MRI imaging plays a very important role in distinguishing abscess loculation from malignancy. The authors present the case of a 13-year-old boy with pain in the right heel for few months. Radiograph of the right foot revealed a lucent focus with sclerotic margin in the right calcaneum. MRI T1-weighted images were inconclusive of penumbra sign to characterise abscess cavity due to the small volume lesion. Whole-body (18)F-FDG PET/CT scan showed multiple small avid lesions at the margin of the sclerotic rim in the right calcaneum. Final diagnosis of Brodie's abscess with Klebsiella culture was confirmed via bone debridement.

Abstract Image

Abstract Image

Abstract Image

F-FDG PET/CT作为MRI诊断布罗迪脓肿的潜在辅助手段。
慢性骨髓炎(布罗迪脓肿)本质上是一个诊断问题,与其他良性和恶性骨病变区分起来可能相当困难。早期诊断的布罗迪脓肿被认为是重要的,因为疾病有良好的治疗潜力后,适当的抗生素治疗。最近,使用F-FDG的PET/CT在骨感染成像中占据了中心位置,尽管关于其在表征Brodie脓肿特征方面的作用的文献非常少。另一方面,众所周知,MRI成像在鉴别脓肿定位与恶性肿瘤方面起着非常重要的作用。作者提出的情况下,一个13岁的男孩在右脚跟疼痛了几个月。右脚x线片显示右跟骨有清晰的病灶,边缘有硬化。由于病灶体积小,MRI t1加权图像不确定半影征象为脓肿腔的特征。全身(18)F-FDG PET/CT扫描显示右跟骨硬化边缘有多个小的明显病变。最终诊断为克雷伯氏菌培养布罗迪脓肿通过骨清创。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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