Benedikt Hoeh, Rocco S Flammia, Lukas Hohenhorst, Gabriele Sorce, Francesco Chierigo, Zhe Tian, Fred Saad, Michele Gallucci, Alberto Briganti, Carlo Terrone, Shahrokh F Shariat, Markus Graefen, Derya Tilki, Luis A Kluth, Philipp Mandel, Andreas Becker, Felix K H Chun, Pierre I Karakiewicz
{"title":"Non-organ confined stage and upgrading rates in exclusive PSA high-risk prostate cancer patients.","authors":"Benedikt Hoeh, Rocco S Flammia, Lukas Hohenhorst, Gabriele Sorce, Francesco Chierigo, Zhe Tian, Fred Saad, Michele Gallucci, Alberto Briganti, Carlo Terrone, Shahrokh F Shariat, Markus Graefen, Derya Tilki, Luis A Kluth, Philipp Mandel, Andreas Becker, Felix K H Chun, Pierre I Karakiewicz","doi":"10.1002/pros.24313","DOIUrl":null,"url":null,"abstract":"The pathological stage of prostate cancer with high‐risk prostate‐specific antigen (PSA) levels, but otherwise favorable and/or intermediate risk characteristics (clinical T‐stage, Gleason Grade group at biopsy [B‐GGG]) is unknown. We hypothesized that a considerable proportion of such patients will exhibit clinically meaningful GGG upgrading or non‐organ confined (NOC) stage at radical prostatectomy (RP).","PeriodicalId":501684,"journal":{"name":"The Prostate","volume":" ","pages":"687-694"},"PeriodicalIF":0.0000,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Prostate","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/pros.24313","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/2/21 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
The pathological stage of prostate cancer with high‐risk prostate‐specific antigen (PSA) levels, but otherwise favorable and/or intermediate risk characteristics (clinical T‐stage, Gleason Grade group at biopsy [B‐GGG]) is unknown. We hypothesized that a considerable proportion of such patients will exhibit clinically meaningful GGG upgrading or non‐organ confined (NOC) stage at radical prostatectomy (RP).