Chest radiography evaluation in patients admitted with confirmed COVID-19 infection, in a resource limited South African isolation hospital.

Pub Date : 2022-01-17 eCollection Date: 2022-01-01 DOI:10.4102/sajr.v26i1.2262

Sereesh Moodley, Tanusha Sewchuran

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引用次数: 5

Abstract

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the subsequent global outbreak (coronavirus disease 2019 [COVID-19]) was declared a public health emergency in January 2020. Recent radiologic literature regarding COVID-19 has primarily focused on Computed Tomography (CT) chest findings, with chest radiography lacking in comparison.

Objectives: To describe the demographic profile of adult patients with COVID-19 pneumonia requiring hospital admission. To describe and quantify the imaging spectrum on chest radiography using a severity index, and to correlate the severity of disease with prognosis.

Method: Retrospective review of chest radiographs and laboratory records in patients admitted to a South African tertiary hospital with confirmed COVID-19 infection. The chest X-rays were systematically reviewed for several radiographic features, which were then quantified using the Brixia scoring system, and correlated to the patient's outcome.

Results: A total of 175 patients (mean age: 53.34 years) admitted with COVID-19 were included. Ground glass opacification (98.9%), consolidation (86.3%), and pleural effusion (29.1%) was commonly found. Involvement of bilateral lung fields (96.6%) with no zonal predominance (61.7%), was most prevalent. Correlation between the Brixia score and outcome was found between severe disease and death (odds ratio [OR]: 12.86; 95% confidence interval [CI]: 1.58-104.61). Many patients had unknown TB (71.4%) and HIV (72.6%) statuses.

Conclusion: In this study population, ground glass opacification, consolidation, and pleural effusions, with bilateral lung involvement and no zonal predominance were the most prevalent findings in proven COVID-19 infection. Quantification using the Brixia scoring system may assist with timeous assessment of disease severity in COVID-19 positive patients, as an overall predicator of clinical outcome.

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在南非一家资源有限的隔离医院，对确诊COVID-19感染患者的胸片评估。

背景:2020年1月，严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)及其随后的全球暴发(冠状病毒病2019 [COVID-19])被宣布为突发公共卫生事件。最近关于COVID-19的放射学文献主要集中在计算机断层扫描(CT)胸部发现，胸片缺乏比较。目的:描述需要住院治疗的成年COVID-19肺炎患者的人口统计学特征。使用严重程度指数描述和量化胸片成像谱，并将疾病严重程度与预后联系起来。方法:回顾性分析南非某三级医院确诊COVID-19感染患者的胸片和实验室记录。系统地检查胸部x光片的几个影像学特征，然后使用Brixia评分系统对其进行量化，并将其与患者的预后相关联。结果:共纳入175例新冠肺炎患者，平均年龄53.34岁。常见的有磨玻璃混浊(98.9%)、实变(86.3%)和胸腔积液(29.1%)。累及双侧肺野(96.6%)，无分区优势(61.7%)，最常见。重度疾病与死亡之间存在Brixia评分与预后的相关性(优势比[OR]: 12.86;95%置信区间[CI]: 1.58-104.61)。许多患者有未知的结核病(71.4%)和艾滋病毒(72.6%)状态。结论:在本研究人群中，经证实的COVID-19感染中最常见的表现是磨玻璃混浊、实变和胸膜积液，伴双侧肺受累，无地带性优势。使用Brixia评分系统进行量化可以帮助及时评估COVID-19阳性患者的疾病严重程度，作为临床结果的总体预测指标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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