Yuancong Jiang, Deqiang Kong, Xiaolong Miao, Xing Yu, Zelai Wu, Han Liu, Weihua Gong
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引用次数: 2
Abstract
Inflammatory bowel disease (IBD), including Crohn disease and ulcerative colitis, with multifactorial etiologies has led to a global health-associated burden in many countries. Substantial efforts are devoted to understand the pathogenesis, behavioral and environmental triggers, which may be specifically valuable for the treatment of IBD. The specific pathogenesis underlying IBD is as yet incompletely understood. The use of anti-cytokine therapy and small molecule agents targeting the immune system is thought to restore the body's intestinal barrier function and relieve inflammation with manageable adverse effects. In this review, we report recent advances in anti-cytokine therapy and treatment with small molecule agents for the management of IBD.
期刊介绍：
The journal that brings together all areas of work involving cytokines.
European Cytokine Network is an electronic journal that publishes original articles and abstracts every quarter to provide an essential bridge between researchers and clinicians with an interest in this cutting-edge field.
The journal has become a must-read for specialists in the field thanks to its swift publication and international circulation.
The journal is referenced in several databases, including Medline, which is testament to its scientific quality.
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