Staple line reinforcement with nebulized cyanoacrylate glue in laparoscopic sleeve gastrectomy: A propensity score-matched study.

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Open medicine (Warsaw, Poland) Pub Date : 2022-01-19 eCollection Date: 2022-01-01 DOI:10.1515/med-2022-0426

Gennaro Martines, Giovanni Tomasicchio, Arcangelo Picciariello, Rigers Dibra, Giuseppe Trigiante, Giuliano Lantone, Donato Francesco Altomare

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引用次数: 1

Abstract

Background: A dreaded complication of laparoscopic sleeve gastrectomy (LSG) is suture leak. The study aimed to assess the efficacy of the nebulized comonomer Glubran 2^® (N-butyl-cyanoacrylate + metacrylosysolfolane) applied to the LSG staple line.

Methods: A propensity-matched comparison analysis was conducted in 125 patients undergoing LSG between 2017 and 2019. Groups included those treated with Glubran^® (group 1, n = 70) and those without Glubran^® treatment (group 2, n = 55).

Results: There were differences in the mean body mass index (44.4 vs 43 kg/m²; P < 0.05) between the groups. There was a non-significant increase in the operative time for group 1 compared with group 2 (97 ± 8 vs 93.8 ± 10.7 min; P = 0.07), with a greater amount of estimated blood loss (94.5 mL vs 87.8; P < 0.01). There were more severe complications in group 2 over group 1 cases (8 vs 0%; P < 0.05), although postoperative bleeding did not differ between the two groups (1.4 vs 5.4%). There were no postoperative leaks in group 1 patients, but there were two leaks in group 2 cases with an increased length of hospital stay in patients with a leak.

Conclusion: Glubran^® LSG support may reduce leak risk without increasing operating time.

查看原文本刊更多论文

用雾化氰基丙烯酸酯胶加固腹腔镜袖胃切除术中的钉线:一项倾向评分匹配的研究。

背景:腹腔镜袖式胃切除术(LSG)的一个可怕的并发症是缝合漏。本研究旨在评估雾化单体Glubran 2®(N-butyl-cyanoacrylate + metacrylosysolfolane)应用于LSG短纤维生产线的效果。方法:对2017年至2019年125例行LSG的患者进行倾向匹配比较分析。组分为经Glubran®治疗组(第1组，n = 70)和未经Glubran®治疗组(第2组，n = 55)。结果:两组患者的平均体重指数(44.4 vs 43 kg/m2;P < 0.05)。与2组相比，1组的手术时间无明显增加(97±8 vs 93.8±10.7 min);P = 0.07)，估计失血量更大(94.5 mL vs 87.8 mL;P < 0.01)。2组并发症发生率高于1组(8% vs 0%;P < 0.05)，但两组术后出血无差异(1.4 vs 5.4%)。1组患者术后无渗漏，2组患者术后有2例渗漏，渗漏患者住院时间延长。结论:Glubran®LSG支架可在不增加操作时间的情况下降低泄漏风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Open medicine (Warsaw, Poland)

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