An Unusual Case of Pancytopenia: The Lessons Learnt.

IF 1.5
Ragesh R Nair, Pawan K Singh, Jeetendra Sharma, Isha Gambhir, Shivangi Khanna, Amit Kumar Jain, Rohan Haldar, Vikrant S Bhar
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Abstract

Pancytopenia is a common hematological abnormality encountered in clinical practice. We here report a 36-year-old male who presented to emergency department with complaints of weakness of bilateral lower limbs, burning sensation in all four limbs with history of loose stools, and vomiting 5 days back. The complete blood count of patient showed pancytopenia with no circulating atypical cells. Bone marrow examination performed showed nonspecific but characteristic findings. After excluding the possibility of infective etiology, a possibility of heavy metal toxicity was suspected in multidisciplinary meeting. The urine and blood levels of arsenic done came out very high, and a diagnosis of arsenic poisoning was made. Patient had multisystemic involvement with features characteristic of arsenic poisoning. The present case was a diagnostic challenge in face of nonforthcoming history. This case beautifully highlighted the importance of multidepartmental approach in such cases to arrive at unerring diagnosis and the unique bone marrow findings, although nonspecific were sufficient enough to indicate the possibility of acute insult to the hematopoiesis. How to cite this article: Nair RR, Singh PK, Sharma J, Gambhir I, Khanna S, Jain AK, et al. An Unusual Case of Pancytopenia: The Lessons Learnt. Indian J Crit Care Med 2022;26(1):141-144.

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一个不寻常的全血细胞减少症病例:吸取教训。
全血细胞减少症是临床常见的血液学异常。我们在此报告一名36岁男性,以双侧下肢无力、四肢烧灼感、稀便史及呕吐5天前来急诊室就诊。患者全血细胞计数显示全血细胞减少,无循环非典型细胞。骨髓检查显示非特异性但特征性的发现。在排除感染病因的可能性后,多学科会议怀疑重金属中毒的可能性。尿液和血液中砷的含量都很高,因此诊断为砷中毒。患者多系统受累,表现为砷中毒。本病例是一个诊断挑战,面对未知的历史。这个病例很好地强调了在这种情况下多部门检查的重要性,以达到准确的诊断和独特的骨髓发现,尽管非特异性足以表明对造血系统的急性损伤的可能性。本文出处:Nair RR, Singh PK, Sharma J, Gambhir I, Khanna S, Jain AK等。一个不寻常的全血细胞减少症病例:吸取教训。中华检验医学杂志;2009;26(1):141-144。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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