A Pediatric Case of Sensory Predominant Guillain-Barré Syndrome Following COVID-19 Vaccination.

Child neurology open Pub Date : 2022-01-25 eCollection Date: 2022-01-01 DOI:10.1177/2329048X221074549
Yunsung Kim, Zahra Zhu, Puneet Kochar, Patrick Gavigan, Divpreet Kaur, Ashutosh Kumar
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引用次数: 10

Abstract

Over six billion doses of Coronavirus Disease 2019 (COVID-19) vaccines have been administered worldwide. Amidst the global COVID-19 vaccination campaign, vaccine-related side effects are of ongoing concern and investigation. According to the Centers for Disease Control and Prevention (CDC) and the United States Department of Health and Human Services, three main conditions in adults have surfaced in association with receiving the COVID-19 vaccines. These include thrombosis with thrombocytopenia syndrome (TTS), a rare syndrome involving venous or arterial thrombosis and thrombocytopenia, Guillain-Barre syndrome (GBS), and myocarditis. While a number of GBS cases in adults have been published, to our knowledge, only one pediatric case of COVID-19 vaccine-related GBS has been reported. Herein we describe a case of sensory predominant GBS following the Pfizer-BioNTech COVID-19 vaccine in a 16-year-old female presenting with bilaterally ascending upper and lower extremity numbness and paresthesia.

Abstract Image

Abstract Image

小儿COVID-19疫苗接种后出现感觉显性格林-巴罗综合征1例
全球已接种了超过60亿剂2019冠状病毒病(COVID-19)疫苗。在全球COVID-19疫苗接种运动中,与疫苗相关的副作用受到持续关注和调查。根据美国疾病控制与预防中心(CDC)和美国卫生与公众服务部的数据,成年人中出现了三种与接种COVID-19疫苗有关的主要情况。这些包括血栓形成伴血小板减少综合征(TTS),一种涉及静脉或动脉血栓形成和血小板减少症的罕见综合征,格林-巴利综合征(GBS)和心肌炎。虽然已发表了许多成人GBS病例,但据我们所知,仅报告了一例与COVID-19疫苗相关的儿童GBS病例。在此,我们描述了一位16岁的女性,在接种了辉瑞- biontech COVID-19疫苗后,出现了以感觉为主的GBS,表现为双侧上肢和下肢麻木和感觉异常。
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