Shashank Kumar Maurya, Amit Bhattacharya, Pooja Shukla, Rajnikant Mishra
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引用次数: 2
Abstract
The sudden outbreak of the novel coronavirus infection (COVID-19, SARS-CoV-2 virus) is posing a significant threat by affecting millions of people across the globe showing mild to severe symptoms of pneumonia and acute respiratory distress. The absence of precise information on primary transmission, diagnosis, prognosis, and therapeutics for patients with COVID-19 makes prevention and control tough. In the current scenario, only supportive treatment is available, which in turn possess a biggest challenge for scientists to develop specific drugs and vaccines for COVID-19. Further, India, with the second largest populated country and fluctuating climatic conditions quarterly, has high vulnerability towards COVID-19 infection. Thus, this highlights the importance of a better understanding of the COVID-19 infection, pathology, diagnosis and its treatment. The present review article has been intended to discuss the COVID-19 biology, mechanism of infection in humans with primary effects on pregnancy, the nervous system, diabetes, and cardiovascular disease. The article will also discuss the drug repurposing strategy as an alternative line of treatment and clinical practices recommended by the World Health Organization and other government agencies and represent the COVID-19 scenario with the Indian context.
期刊介绍：
The Proceedings of the National Academy of Sciences, India, Section B: Biological Sciences, is one of the oldest journals of India, launched in the year 1930, by the National Academy of Sciences, India (the Oldest Science Academy of India). The research/review papers of different fields of science, e.g. Agriculture Sciences (Agriculture, Animal Husbandry, Fisheries, Forestry, Agric. Toxicology, Soil Science, Plant Protection, Post Harvest Technology, and Agricultural Engineering), Animal Sciences (Structural, Developmental, Functional, Genetical, Ecological, Behavioural, Taxonomical and Evolutionary Aspects), Biochemistry, Biophysics, Biotechnology (including Molecular and Cell Biology, Structural and Functional Studies, Microbiology and Immunology), Medical & Forensic Sciences (Basic and Clinical Medical Sciences, Pharmacology, Anthropology, Psychology and Forensic Sciences, Human genetics, Reproduction Biology, Neurosciences and Molecular Medicine) and Plant Sciences (Structural, Developmental, Functional, Genetical, Ecological, Taxonomical and Evolutionary Aspects), are published in this journal for dissemination of the scientific knowledge and research. The papers published are indexed/abstracted by the leading abstracting agencies of the world. The papers are published after critical review and editing by the eminent experts of the concerned subject area; therefore, the quality publication is assured once the paper is accepted by the learned referees.
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