[Impact of vaccination against COVID-19 in children aged 5-11 years: a mathematical model.]

IF 0.9 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Revista Espanola De Salud Publica Pub Date : 2022-02-21
David Expósito Singh, Carmen Olmedo Lucerón, Aurora Limia Sánchez, Miguel Guzmán Merino, Jesús Carretero
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引用次数: 0

Abstract

On November 25, 2021, the European Medicines Agency (EMA) authorized the presentation of Comirnaty vaccine (Pfizer-Biontech) for children between 5 and 11 years of age. In our country, this vaccination began on December 15, after it was approved by the Public Health Commission. A mathematical model has been developed to evaluate the possible impact of this vaccination and contribute to assessing the risk-benefit balance. The model parameters were adjusted including all those characteristics that may influence the impact of childhood vaccination. The results indicate this vaccination involves a significant reduction in the number of infections, and to a lesser extent in the number of hospitalizations and deaths. This reduction will be more important in a future epidemic wave, when this population has been fully vaccinated. Mathematical models can be very powerful tools to predict the impact of vaccination in different epidemiological situations, and help to adjust vaccination programs to be more efficient.

[接种COVID-19疫苗对5-11岁儿童的影响:一个数学模型]
2021年11月25日,欧洲药品管理局(EMA)批准了用于5至11岁儿童的Comirnaty疫苗(Pfizer-Biontech)。在我国,这种疫苗接种在获得公共卫生委员会批准后,于12月15日开始。已经开发了一个数学模型来评估这种疫苗接种的可能影响,并有助于评估风险-收益平衡。对模型参数进行了调整,包括所有可能影响儿童疫苗接种效果的特征。结果表明,这种疫苗接种大大减少了感染人数,并在较小程度上减少了住院和死亡人数。在未来的流行病浪潮中,当这些人群已完全接种疫苗时,这种减少将更为重要。数学模型可以成为预测不同流行病学情况下疫苗接种影响的有力工具,并有助于调整疫苗接种规划以提高效率。
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来源期刊
Revista Espanola De Salud Publica
Revista Espanola De Salud Publica PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
2.00
自引率
0.00%
发文量
106
审稿时长
12 weeks
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