Case of Renal Aspergillosis after Heart Transplant: Diagnosis and Treatment.

IF 0.3 Q4 TRANSPLANTATION

International Journal of Organ Transplantation Medicine Pub Date : 2021-01-01

M Mahdavi, G Mortaz-Hejri, H Shahzadi, H R Pouraliakbar, A Amin, M Hesami, B Naghavi

引用次数: 0

Abstract

Invasive aspergillosis (IA) is a severe complication after heart transplantation (HTx), with a high mortality rate. Invasive pulmonary aspergillosis (IPA) is the most common presentation. We herein describe a unique case of Renal aspergillosis (RAsp) diagnosed on month 10 post-HTx with no known risk factors for IPA in cardiac transplant recipients. The diagnosis of RAsp was made based on radiographic findings, renal biopsy, and tissue cultures. The patient initially received combined antifungal therapy (caspofungin and voriconazole) without radical or partial nephrectomy, followed by voriconazole maintenance monotherapy with favorable clinical outcomes.

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心脏移植后肾曲霉病1例:诊断与治疗。

侵袭性曲霉病(Invasive aspergilllosis, IA)是心脏移植术后的严重并发症，死亡率高。侵袭性肺曲霉病(IPA)是最常见的表现。我们在此描述一个独特的病例肾曲霉病(RAsp)诊断后10个月htx没有已知的危险因素IPA心脏移植受者。RAsp的诊断是基于影像学表现、肾活检和组织培养。患者最初接受联合抗真菌治疗(卡泊芬净和伏立康唑)，未进行完全或部分肾切除术，随后接受伏立康唑维持单药治疗，临床结果良好。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Organ Transplantation Medicine TRANSPLANTATION-

CiteScore

1.60

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： The International Journal of Organ Transplantation Medicine (IJOTM) is a quarterly peer-reviewed English-language journal that publishes high-quality basic sciences and clinical research on transplantation. The scope of the journal includes organ and tissue donation, procurement and preservation; surgical techniques, innovations, and novelties in all aspects of transplantation; genomics and immunobiology; immunosuppressive drugs and pharmacology relevant to transplantation; graft survival and prevention of graft dysfunction and failure; clinical trials and population analyses in the field of transplantation; transplant complications; cell and tissue transplantation; infection; post-transplant malignancies; sociological and ethical issues and xenotransplantation.