Nonpharmacological measures to prevent allergic symptoms in pollen allergy: A critical review.

Allergologie Select Pub Date : 2021-12-01 eCollection Date: 2021-01-01 DOI:10.5414/ALX02294E
Karl-Christian Bergmann, Markus Berger, Ludger Klimek, Oliver Pfaar, Barbora Werchan, Matthias Werchan, Torsten Zuberbier
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Abstract

Allergic rhinoconjunctivitis (hay fever) is the most common chronic disease in all industrialized nations. Therapy consists essentially in the use of anti-allergic and anti-inflammatory drugs, which mostly show a good and quick effect. With allergen-specific immunotherapy, there is also a causal possibility of tolerance induction. There is currently a considerable undersupply, as those affected trivialize the symptoms and often have concerns about long-term drug therapy. There is also great interest in using non-medicinal measures to prevent and/or relieve allergic symptoms on the assumption that these are free from side effects. In this publication, we present non-drug methods for which clinical studies are available in the literature. The methods have varying degrees of effectiveness. An evidence-based comparative assessment between the methods is not possible. There are also hardly any studies in comparison to standard drug therapy. A large number of the interventions consist of allergen reduction, e.g., with air filters, or cleaning of the mucous membranes with nasal irrigation, etc., none of which should be seen as a substitute but as a supplement to drug therapy.

Abstract Image

Abstract Image

预防花粉过敏症状的非药物措施:重要综述。
过敏性鼻结膜炎(花粉症)是所有工业化国家最常见的慢性疾病。治疗方法主要是使用抗过敏和消炎药物,这些药物大多具有良好而快速的疗效。过敏原特异性免疫疗法还有可能诱发耐受。由于患者将症状轻描淡写,而且往往对长期药物治疗心存顾虑,因此目前的药物供应严重不足。此外,人们还对使用非药物措施预防和/或缓解过敏症状产生了浓厚的兴趣,因为这些措施没有副作用。在本刊物中,我们介绍了文献中已有临床研究的非药物方法。这些方法具有不同程度的有效性。我们无法对这些方法进行循证比较评估。与标准药物疗法进行比较的研究也几乎没有。大量干预措施包括减少过敏原,如使用空气过滤器,或通过鼻腔冲洗清洁粘膜等,这些措施都不应被视为药物疗法的替代品,而应被视为药物疗法的补充。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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