Anabolic-Androgenic Steroid Misuse: Mechanisms, Patterns of Misuse, User Typology, and Adverse Effects.

Journal of Sports Medicine Pub Date : 2021-12-10 eCollection Date: 2021-01-01 DOI:10.1155/2021/7497346
Jack B Ding, Marcus Z Ng, Steven S Huang, Mark Ding, Kevin Hu
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引用次数: 6

Abstract

Anabolic-androgenic steroids (AAS) encompass a broad group of natural and synthetic androgens. AAS misuse is highly prevalent on a global scale, with the lifetime prevalence of AAS misuse in males being estimated to be around 6%, with 15 to 25% of male gym attendees using it at any one time. AAS are associated with sudden cardiac death, neuropsychiatric manifestations, and infertility. The average AAS user is unlikely to voluntarily declare their usage to a physician, with around 1 in 10 actively engaging in unsafe injection techniques. The aim of this paper is to review the current evidence base on AAS with emphasis on mechanisms of action, adverse effects, and user profiles that are most likely to engage in AAS misuse. This paper also reviews terminologies and uses methods specific to the AAS user community.

合成代谢-雄激素类固醇滥用:机制、滥用模式、使用者类型和不良影响。
合成代谢雄激素类固醇(AAS)包括一大类天然的和合成的雄激素。AAS滥用在全球范围内非常普遍,男性终生滥用AAS的比例估计在6%左右,15%到25%的男性健身房参与者在任何时候都使用它。AAS与心源性猝死、神经精神表现和不孕症有关。平均AAS使用者不太可能主动向医生申报他们的使用情况,大约十分之一的人积极使用不安全的注射技术。本文的目的是回顾目前基于AAS的证据,重点介绍AAS的作用机制、不良影响和最有可能滥用AAS的用户概况。本文还回顾了术语,并使用了特定于AAS用户社区的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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18 weeks
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