The first SARS-CoV-2 wave among pregnant women in Italy: results from a prospective population-based study.

IF 1.1 4区医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Annali dell'Istituto superiore di sanita Pub Date : 2021-10-01 DOI:10.4415/ANN_21_04_02

Serena Donati, Edoardo Corsi, Alice Maraschini, Michele Antonio Salvatore

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引用次数: 5

Abstract

Introduction: This study aimed to estimate the incidence of SARS-CoV-2 infection among pregnant women during the first pandemic wave in Italy, and to describe COVID-19 disease characteristics and maternal and perinatal outcomes.

Materials and methods: National population-based prospective cohort study collecting information on women with SARS-CoV-2 diagnosis, confirmed within 7 days from hospital admission.

Results: The national SARS-CoV-2 rate was 6.04 per 1,000 births (95% CI 5.62-6.49) among pregnant women and 7.54 (95% CI 7.47-7.61) among women in reproductive age. 72.1% of the cohort developed mild COVID-19 disease without pneumonia nor need for ventilatory support. Severe disease was significantly associated with women's previous comorbidities (OR 2.55; 95% CI 0.98-6.90), obesity (OR 4.76; 95% CI 1.79-12.66) and citizenship from High Migration Pressure Countries (OR 3.43; 95% CI 1.27-9.25).

Conclusions: During the first pandemic wave in Italy, the SARS-CoV-2 rate among pregnant women was lower compared to that detected among women of reproductive age, and risks of severe COVID-19 disease and adverse maternal and perinatal outcomes were rare.

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意大利孕妇中的第一次SARS-CoV-2浪潮:一项基于人群的前瞻性研究的结果

前言:本研究旨在估计意大利第一波大流行期间孕妇中SARS-CoV-2感染的发生率，并描述COVID-19疾病特征和孕产妇和围产期结局。材料和方法:以全国人群为基础的前瞻性队列研究，收集入院后7天内确诊为SARS-CoV-2的妇女的信息。结果:全国孕妇SARS-CoV-2感染率为6.04‰(95% CI 5.62 ~ 6.49)，育龄妇女为7.54‰(95% CI 7.47 ~ 7.61)。72.1%的队列出现轻度COVID-19疾病，无肺炎，不需要呼吸支持。严重疾病与女性既往合并症显著相关(OR 2.55;95% CI 0.98-6.90)，肥胖(OR 4.76;95% CI 1.79-12.66)和来自高移民压力国家的公民身份(OR 3.43;95% ci 1.27-9.25)。结论:在意大利第一波大流行期间，孕妇中SARS-CoV-2的检出率低于育龄妇女，发生严重COVID-19疾病和孕产妇及围产期不良结局的风险较低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annali dell'Istituto superiore di sanita PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

3.80

自引率

4.80%

发文量

审稿时长

>12 weeks

期刊介绍： Annali dell’Istituto Superiore di Sanità is a peer reviewed quarterly science journal which publishes research articles in biomedicine, translational research and in many other disciplines of the health sciences. The journal includes the following material: original articles, reviews, commentaries, editorials, brief and technical notes, book reviews. The publication of Monographic Sections has been discontinued. In case you wish to present a small number of coordinated contributions on specific themes concerning priorities in public health, please contact the Editorial office. The journal is in English.