Autologous Bone Marrow-Derived Chondrocytes for Patients with Knee Osteoarthritis: A Randomized Controlled Trial.

IF 1.2 Q3 ORTHOPEDICS
Advances in Orthopedics Pub Date : 2021-11-20 eCollection Date: 2021-01-01 DOI:10.1155/2021/2146722
Mir Sadat-Ali, Abdallah S AlOmran, Sulaiman A AlMousa, Hasan N AlSayed, Khalid W AlTabash, Mohammed Q Azam, Tarek M Hegazi, Sadananda Acharya
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引用次数: 1

Abstract

Results: There were a total of 60 patients who were followed up. Three patients in Group II were removed from the analysis as they underwent total knee arthroplasty (TKA). A notably significant improvement was noticed in the ABMDC group on all scores of VAS and MKSSSF with P < 0.0001. The control group continued to be dissatisfied with the treatment they were taking.

Conclusions: This study reveals that a single injection of 5 million of ABMDC was efficient in reducing the symptoms, improving the functional score and betterment of QOL.

Abstract Image

Abstract Image

自体骨髓来源的软骨细胞治疗膝骨关节炎:一项随机对照试验。
结果:共随访60例患者。II组的3例患者因接受全膝关节置换术(TKA)而被从分析中剔除。ABMDC组VAS和MKSSSF评分均有显著改善(P < 0.0001)。对照组继续对他们所接受的治疗不满意。结论:单次注射500万ABMDC可有效减轻症状,改善功能评分,改善生活质量。
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来源期刊
CiteScore
2.40
自引率
0.00%
发文量
36
审稿时长
21 weeks
期刊介绍: Advances in Orthopedics is a peer-reviewed, Open Access journal that provides a forum for orthopaedics working on improving the quality of orthopedic health care. The journal publishes original research articles, review articles, and clinical studies related to arthroplasty, hand surgery, limb reconstruction, pediatric orthopaedics, sports medicine, trauma, spinal deformities, and orthopaedic oncology.
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