A sudden creatinine increase: A case report.

IF 3.8 3区医学 Q1 MEDICAL LABORATORY TECHNOLOGY

Biochemia Medica Pub Date : 2022-02-15 DOI:10.11613/BM.2022.011002

Bernhard Strasser, Sebastian Strasser, Josef Tomasits

引用次数: 0

Abstract

Creatinine and estimated glomerular filtration rate (eGFR) are first-line laboratory parameters in the diagnosis of various renal diseases. In recent decades, cystatin C (cysC) has furthered the laboratory repertoire regarding renal status assessment and has been implemented in many clinical guidelines. Accordingly, with the establishment of cysC as a renal routine biomarker, further opportunities for assessing eGFR have been attained. Nevertheless, various limitations are still associated with cysC and creatinine analysis. Preanalytical errors could cause false results in both biomarkers. In our case, we were confronted with implausibly elevated creatinine levels due to preanalytical errors.

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肌酸酐突然升高1例。

肌酐和估计肾小球滤过率(eGFR)是诊断各种肾脏疾病的一线实验室参数。近几十年来，胱抑素C (cystatin C, cysC)在肾脏状态评估方面得到了进一步的实验室应用，并在许多临床指南中得到了应用。因此，随着cysC作为肾脏常规生物标志物的确立，进一步获得了评估eGFR的机会。然而，各种限制仍然与cysC和肌酐分析有关。分析前错误可能导致两种生物标志物的错误结果。在我们的病例中，由于分析前的错误，我们面临着令人难以置信的肌酐水平升高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biochemia Medica 医学-医学实验技术

CiteScore

5.50

自引率

3.00%

发文量

审稿时长

>12 weeks

期刊介绍： Biochemia Medica is the official peer-reviewed journal of the Croatian Society of Medical Biochemistry and Laboratory Medicine. Journal provides a wide coverage of research in all aspects of clinical chemistry and laboratory medicine. Following categories fit into the scope of the Journal: general clinical chemistry, haematology and haemostasis, molecular diagnostics and endocrinology. Development, validation and verification of analytical techniques and methods applicable to clinical chemistry and laboratory medicine are welcome as well as studies dealing with laboratory organization, automation and quality control. Journal publishes on a regular basis educative preanalytical case reports (Preanalytical mysteries), articles dealing with applied biostatistics (Lessons in biostatistics) and research integrity (Research integrity corner).