Comparative Analysis of the Risk Factors Influencing Recovery of Function from Oculomotor Nerve Palsy in Unruptured and Ruptured Posterior Communicating Artery Aneurysms.

IF 0.9 4区医学 Q4 CLINICAL NEUROLOGY

Turkish neurosurgery Pub Date : 2024-01-01 DOI:10.5137/1019-5149.JTN.32677-20.1

Vikas Chandra Jha, Vivek Sinha, Vishal Abhijit, Neeraj Jha, Saraj Kumar Singh

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Abstract

Aim: To assess the risk factors and simultaneously compared the benefits of procedures (clipping vs. coiling) in the recovery of function from oculomotor nerve palsy (OMNP) between cases with unruptured and ruptured posterior communicating artery (PCOM) aneurysms.

Material and methods: Among the 225 cases of aneurysm treated in our department between July 2018 and February 2020, 25 patients with PCOM aneurysm with OMNP (unruptured: n=13; ruptured: n=12) were retrospectively analysed.

Results: The average duration from onset of symptoms to treatment in unruptured PCOM aneurysm cases was 13.33 ± 3.76 days compared with 7.41 ± 2.42 days in ruptured aneurysm cases. Moreover, an 80% improvement was observed when OMNP was treated within 17 days with the earliest improvement noticed in 33.05 ± 18.75 days in unruptured aneurysm cases compared with 39.66 ± 31.75 days in ruptured PCOM aneurysm cases. Stepwise logistic regression analysis revealed that the type of aneurysm (better recovery in unruptured aneurysm cases) was a significant risk factor (p=0.0126), but not the procedure (clipping vs. coiling) performed, for function recovery from OMNP.

Conclusion: Patients with unruptured PCOM aneurysms with OMNP have a better recovery rate than those with ruptured PCOM aneurysms. No procedural (clipping vs. coiling) advantages were observed on the recovery of function from OMNP. Transmitted pulsation reduction significantly affects the recovery of function from OMNP.

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影响未破裂和破裂的后交通动脉瘤患者眼运动神经麻痹功能恢复的风险因素比较分析。

目的：评估未破裂和破裂的后交通动脉（PCOM）动脉瘤病例的风险因素，同时比较手术（夹闭与卷绕）对眼动神经麻痹（OMNP）功能恢复的益处：在我科2018年7月至2020年2月期间收治的225例动脉瘤患者中，回顾性分析了25例伴有OMNP的PCOM动脉瘤患者（未破裂：n=13；破裂：n=12）：未破裂的PCOM动脉瘤病例从症状出现到接受治疗的平均时间为（13.33±3.76）天，而破裂的动脉瘤病例为（7.41±2.42）天。此外，如果在 17 天内治疗 OMNP，患者的病情改善率为 80%，未破裂动脉瘤患者的病情改善率为（33.05 ± 18.75）天，而破裂 PCOM 动脉瘤患者的病情改善率为（39.66 ± 31.75）天。逐步逻辑回归分析显示，动脉瘤类型（未破裂动脉瘤病例恢复更好）是影响 OMNP 功能恢复的一个重要风险因素（p=0.0126），而不是所实施的手术（夹闭与卷绕）：结论：未破裂的 PCOM 动脉瘤患者的 OMNP 恢复率高于破裂的 PCOM 动脉瘤患者。在 OMNP 的功能恢复方面，没有观察到任何程序上的优势（夹闭与卷绕）。减少传导搏动对 OMNP 的功能恢复有很大影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Turkish neurosurgery 医学-临床神经学

CiteScore

1.50

自引率

12.50%

发文量

126

审稿时长

2 months

期刊介绍： Turkish Neurosurgery is a peer-reviewed, multidisciplinary, open access and totally free journal directed at an audience of neurosurgery physicians and scientists. The official language of the journal is English. The journal publishes original articles in the form of clinical and basic research. Turkish Neurosurgery will only publish studies that have institutional review board (IRB) approval and have strictly observed an acceptable follow-up period. With the exception of reference presentation, Turkish Neurosurgery requires that all manuscripts be prepared in accordance with the Uniform Requirements for Manuscripts Submitted to Biomedical Journals.