[Correlation between insufficiency or deficiency of vitamin D levels and interleukins 1β and 6].

Q3 Medicine

Revista alergia Mexico Pub Date : 2021-07-01 DOI:10.29262/ram.v68i3.885

Luis Fernando Zavala-Jonguitud, Juan Carlos Anda, Miguel Guillermo Flores-Padilla, Carla Pérez, José Daniel Juárez-Villa

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Abstract

Objectives: The primary objective of this study was to define the relationship between vitamin D levels and interleukins (IL) 1β and 6 as inflammatory markers in a healthy population. As a secondary objective, to measure the prevalence of insufficiency/ deficiency of vitamin D in the same population.

Methods: A sample of 43 healthy blood donors, without chronic-degenerative, inflammatory, or infectious diseases, and without obesity, was selected. Serum levels of IL-1β and IL-6 were measured in individuals with insufficiency or deficiency of vitamin D. The correlation between vitamin D and interleukins was measured using Spearman's rho.

Results: No correlation was found between levels of vitamin D and interleukins. In addition, a prevalence of insufficiency/deficiency of vitamin D was found in 95.3% of the sample.

Conclusions: In healthy subjects with deficiency or insufficiency of vitamin D, there is no association between the levels of this vitamin and IL-1β and IL-6.

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[维生素D水平不足或缺乏与白细胞介素1β和6的相关性]。

目的:本研究的主要目的是确定健康人群中维生素D水平与作为炎症标志物的白细胞介素(IL) 1β和6之间的关系。作为次要目标，测量同一人群中维生素D不足/缺乏的流行程度。方法:选取43名健康献血者，无慢性退行性疾病、炎症或传染病，无肥胖。在维生素D不足或缺乏的个体中测定血清中IL-1β和IL-6的水平。用Spearman's rho法测定维生素D与白细胞介素的相关性。结果:维生素D水平与白细胞介素水平无相关性。此外，在95.3%的样本中发现了维生素D不足/缺乏的普遍现象。结论:在维生素D缺乏或不足的健康受试者中，维生素D水平与IL-1β和IL-6之间没有关联。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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