Optimizing prognosis in atrial fibrillation: A call to action in Portugal

Jorge Ferreira , Natália António , Nuno Cortez-Dias , Luciana Ricca Gonçalves , João Sargento-Freitas , Pedro von Hafe , Victor Gil
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引用次数: 3

Abstract

Atrial fibrillation (AF), the most common arrhythmia in the adult population worldwide, represents a significant burden in terms of cardiovascular mortality and morbidity and has repercussions on health economics. Oral anticoagulation (OAC) is key to stroke prevention in AF and, in recent years, results from landmark clinical trials of non-vitamin K oral anticoagulants (NOAC) have triggered a paradigm shift in thrombocardiology. Despite these advances, there is still a significant residual vascular risk associated with silent AF, bleeding, premature sudden death and heart failure.

The authors review AF epidemiologic data, the importance of new tools for early AF detection, the current role of catheter ablation for rhythm control in AF, the state-of-the-art in periprocedural OAC, the optimal management of major bleeding, the causes of residual premature death and future strategies for improvements in AF prognosis.

优化房颤的预后:在葡萄牙呼吁采取行动
房颤(AF)是全世界成年人中最常见的心律失常,在心血管死亡率和发病率方面是一个重大负担,并对卫生经济学产生了影响。口服抗凝剂(OAC)是预防房颤卒中的关键,近年来,非维生素K口服抗凝剂(NOAC)具有里程碑意义的临床试验结果引发了血栓心脏病学的范式转变。尽管取得了这些进展,但仍存在与无症状房颤、出血、过早猝死和心力衰竭相关的显著残留血管风险。作者回顾了房颤流行病学资料、房颤早期检测新工具的重要性、导管消融在房颤心律控制中的作用、围手术期OAC的最新进展、大出血的最佳处理、残余过早死亡的原因以及改善房颤预后的未来策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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