Medical Management, Orofacial Findings, and Dental Care for the Patient with Parkinson's Disease.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2021-06-01
Braedan R J Prete, Aviv Ouanounou
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Abstract

Parkinson's disease (PD) is the second most prevalent neurodegenerative disease in North America, next to Alzheimer's disease. Patients who suffer from PD typically present with neuromuscular, cognitive, postural and psychiatric deficits, which make oral hygiene challenging, but extremely important. Although the cardinal signs of PD are movement-related, manifestations in the orofacial complex are ubiquitous. Weakened facial musculature, gaunt appearance, tremors of the tongue, lips and eyes, erratic mandibular movements, bruxism, xerostomia, sialorrhea, dysphagia, dysgeusia and glossitis are examples of the plethora of atypical orofacial findings associated with PD. Further complications, including angular cheilosis, attrition, temporomandibular joint disorders, burning mouth syndrome, hyposmia and hypophonia, may arise as a consequence of these orofacial manifestations. The effects of PD on the orofacial complex may result in poor nutritional habits, which can exacerbate weight loss and contribute to a negative impact on physical, psychosocial and emotional health. Dentists should be able to identify signs of PD systemically, including but not limited to the orofacial region, to optimize the management of PD patients. Here, we report practical recommendations for the medical and dental management of patients with PD in accordance with the most recently published clinical practice guidelines.

帕金森氏病患者的医疗管理、口腔面部表现和牙科护理。
帕金森病(PD)是北美第二常见的神经退行性疾病,仅次于阿尔茨海默病。患有PD的患者通常表现为神经肌肉,认知,姿势和精神缺陷,这使得口腔卫生具有挑战性,但非常重要。虽然PD的主要症状与运动有关,但在口面部复合体的表现是普遍存在的。面部肌肉组织减弱,外观憔悴,舌头、嘴唇和眼睛颤抖,下颌运动不稳定,磨牙,口干,唾液,吞咽困难,发音困难和舌炎是与PD相关的大量非典型口腔面部表现的例子。进一步的并发症,包括角型唇裂、磨损、颞下颌关节紊乱、灼口综合征、低通气和低声音,都可能作为这些口腔面部表现的结果而出现。PD对口腔面部复合体的影响可能导致不良的营养习惯,这可能加剧体重减轻,并对身体、社会心理和情绪健康产生负面影响。牙医应该能够系统地识别PD的迹象,包括但不限于口腔面部区域,以优化PD患者的管理。在这里,我们根据最新出版的临床实践指南报告PD患者的医疗和牙科管理的实用建议。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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