Acute Stroke due to Vertebral Artery Dissection in Giant Cell Arteritis.

Case Reports in Rheumatology Pub Date : 2021-06-30 eCollection Date: 2021-01-01 DOI:10.1155/2021/5518541
Marlene Marte Furment, Sandra Antigua Jimenez, Sangeetha Pabolu
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引用次数: 3

Abstract

The diagnosis of giant cell arteritis (GCA) when presenting with atypical features such as stroke is very challenging. Only 0.17% of first-ever strokes are caused by GCA, a life-threatening condition when left untreated. Very few cases have been reported on giant cell arteritis leading to acute stroke due to vertebral artery dissection. We present a case of a 76-year-old female with no medical history who presented with sudden onset right visual loss and left hemiparesis. She had been initially treated for acute stroke and upon further workup was found to have left vertebral artery dissection. She had erythrocyte sedimentation rate (ESR) of 71 mm/h, and bilateral temporal artery biopsy was consistent with giant cell arteritis. Patient received high doses of methylprednisolone which resolved her hemiparesis, but her vision loss did not improve. Stroke in the presence of significant involvement of vertebral arteries should raise suspicion of GCA especially if classic symptoms preceded stroke event. High clinical suspicion is required to prevent delay in diagnosis and treatment.

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巨细胞动脉炎所致椎动脉夹层急性卒中。
巨细胞动脉炎(GCA)当表现为非典型特征如中风时,诊断是非常有挑战性的。只有0.17%的首次中风是由GCA引起的,如果不及时治疗,这是一种危及生命的疾病。由于椎动脉夹层导致巨细胞动脉炎导致急性脑卒中的病例报道很少。我们报告一例76岁女性,无病史,以突发性右视力丧失和左偏瘫为主要表现。她最初接受急性中风治疗,进一步检查发现左椎动脉夹层。她的红细胞沉降率(ESR)为71 mm/h,双侧颞动脉活检符合巨细胞动脉炎。患者接受大剂量甲基强的松龙治疗,偏瘫得以缓解,但视力减退未见改善。明显累及椎动脉的卒中应引起对GCA的怀疑,特别是在卒中发生前出现经典症状的情况下。需要高度的临床怀疑,以防止延误诊断和治疗。
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