Delay in budget allocation for vaccination and awareness induces chaos in an infectious disease model.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Arvind Kumar Misra, Rajanish Kumar Rai, Pankaj Kumar Tiwari, Maia Martcheva
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引用次数: 6

Abstract

In this paper, we propose a model to assess the impacts of budget allocation for vaccination and awareness programs on the dynamics of infectious diseases. The budget allocation is assumed to follow logistic growth, and its per capita growth rate increases proportional to disease prevalence. An increment in per-capita growth rate of budget allocation due to increase in infected individuals after a threshold value leads to onset of limit cycle oscillations. Our results reveal that the epidemic potential can be reduced or even disease can be eradicated through vaccination of high quality and/or continuous propagation of awareness among the people in endemic zones. We extend the proposed model by incorporating a discrete time delay in the increment of budget allocation due to infected population in the region. We observe that multiple stability switches occur and the system becomes chaotic on gradual increase in the value of time delay.

疫苗接种和意识预算分配的延迟导致传染病模型的混乱。
在本文中,我们提出了一个模型来评估疫苗接种和意识计划的预算分配对传染病动态的影响。假定预算分配遵循后勤增长,其人均增长率与疾病流行率成正比。在一个阈值之后,由于感染个体的增加,预算分配的人均增长率增加,导致极限环振荡的开始。我们的研究结果表明,通过高质量的疫苗接种和/或在流行区人民中不断宣传,可以减少甚至根除疾病的流行潜力。我们扩展了所提出的模型,在预算分配增量中加入了一个离散的时间延迟,这是由于区域内受感染人口的影响。我们观察到,随着时滞值的逐渐增大,系统会出现多个稳定性切换,系统变得混沌。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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