Doppler abnormalities and perinatal outcomes in pregnant women with early-onset fetal growth restriction.

IF 1.6
Cesaltina Soares Muniz, Beatriz Frota Dias, Paula Vitória Pereira Motoyama, Camila Timbó Catunda Almeida, Francisco Edson de Lucena Feitosa, Edward Araujo Júnior, Júlio Augusto Gurgel Alves
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引用次数: 2

Abstract

Objective: To compare Doppler alterations and perinatal outcomes in pregnant women who evolved with early- and late-onset fetal growth restriction (FGR).

Methods: A retrospective, observational cohort study with pregnant women who evolved with FGR treated between January 2018 and April 2019, in which all live births from singleton pregnancies, over 24 weeks, with FGR ultrasound diagnosis and under 2700 g weight were included in the study.

Results: Pregnancies with early-onset FGR were more associated with hypertensive disorders (p = .00) and placental vascular insufficiency, resulting in a high degree of umbilical artery Doppler involvement (p = .00) in a short period of pregnancy and higher rates of adverse perinatal outcomes (p = .00). The time of prenatal follow-up of early- and late-onset FGR cases was similar, but the degree of prematurity of the former made the evolution more unfavorable.

Conclusion: Early-onset FGR had a lower prevalence but was associated with higher maternal and fetal morbidity and mortality than late-onset FGR.

早发型胎儿生长受限孕妇的多普勒异常和围产期结局。
目的:比较早发性和晚发性胎儿生长受限(FGR)孕妇的多普勒变化和围产期结局。方法:对2018年1月至2019年4月期间接受FGR治疗的妊娠妇女进行回顾性观察性队列研究,其中所有单胎妊娠、24周以上、超声诊断为FGR且体重低于2700 g的活产婴儿均纳入研究。结果:早发性FGR妊娠与高血压疾病(p = 0.00)和胎盘血管功能不全的相关性更大,导致妊娠短时间内脐动脉多普勒累及程度高(p = 0.00),围产期不良结局发生率更高(p = 0.00)。早发性FGR和晚发性FGR的产前随访时间相似,但早发性FGR的早产程度更不利于胎儿的发育。结论:早发性FGR患病率较低,但与晚发性FGR相比,其母婴发病率和死亡率较高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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