A Systematic Analysis of Metal and Metalloid Concentrations in Eight Zebrafish Recirculating Water Systems.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2021-08-01 Epub Date: 2021-07-05 DOI:10.1089/zeb.2020.1970

Xavier Langa, Patrick Neuhaus, David Lains, Theodora J Stewart, Nadine Borel, Ana C Certal, Joana F Monteiro, Peter Aleström, Eduardo Diaz, Indre Piragyte, Lars Bräutigam, Rodolfo Vázquez, Ruslan Hlushchuk, Lorenz Gfeller, Adrien Mestrot, Moritz Bigalke, Zoltan M Varga, Nadia Mercader

{"title":"A Systematic Analysis of Metal and Metalloid Concentrations in Eight Zebrafish Recirculating Water Systems.","authors":"Xavier Langa, Patrick Neuhaus, David Lains, Theodora J Stewart, Nadine Borel, Ana C Certal, Joana F Monteiro, Peter Aleström, Eduardo Diaz, Indre Piragyte, Lars Bräutigam, Rodolfo Vázquez, Ruslan Hlushchuk, Lorenz Gfeller, Adrien Mestrot, Moritz Bigalke, Zoltan M Varga, Nadia Mercader","doi":"10.1089/zeb.2020.1970","DOIUrl":null,"url":null,"abstract":"<p><p>Metals and metalloids are integral to biological processes and play key roles in physiology and metabolism. Nonetheless, overexposure to some metals or lack of others can lead to serious health consequences. In this study, eight zebrafish facilities collaborated to generate a multielement analysis of their centralized recirculating water systems. We report a first set of average concentrations for 46 elements detected in zebrafish facilities. Our results help to establish an initial baseline for trouble-shooting purposes, and in general for safe ranges of metal concentrations in recirculating water systems, supporting reproducible scientific research outcomes with zebrafish.</p>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cb/56/zeb.2020.1970.PMC8392081.pdf","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1089/zeb.2020.1970","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/7/5 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 1

Abstract

Metals and metalloids are integral to biological processes and play key roles in physiology and metabolism. Nonetheless, overexposure to some metals or lack of others can lead to serious health consequences. In this study, eight zebrafish facilities collaborated to generate a multielement analysis of their centralized recirculating water systems. We report a first set of average concentrations for 46 elements detected in zebrafish facilities. Our results help to establish an initial baseline for trouble-shooting purposes, and in general for safe ranges of metal concentrations in recirculating water systems, supporting reproducible scientific research outcomes with zebrafish.

Abstract Image

查看原文本刊更多论文

八个斑马鱼循环水系统中金属和类金属浓度的系统分析。

金属和类金属是生物过程的组成部分，在生理和代谢中起着关键作用。然而，过度接触某些金属或缺乏其他金属会导致严重的健康后果。在这项研究中，八个斑马鱼设施合作对其集中循环水系统进行了多元素分析。我们报告了在斑马鱼设施中检测到的46种元素的第一组平均浓度。我们的研究结果有助于建立一个初步的基线，用于故障排除，以及在循环水系统中金属浓度的安全范围，支持斑马鱼可重复的科学研究成果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.