Translational biomarkers in the era of precision medicine.

2区医学 Q1 Chemistry

Advances in Clinical Chemistry Pub Date : 2021-01-01 Epub Date: 2020-10-03 DOI:10.1016/bs.acc.2020.08.002

Laura Bravo-Merodio, Animesh Acharjee, Dominic Russ, Vartika Bisht, John A Williams, Loukia G Tsaprouni, Georgios V Gkoutos

引用次数: 12

Abstract

In this chapter we discuss the past, present and future of clinical biomarker development. We explore the advent of new technologies, paving the way in which health, medicine and disease is understood. This review includes the identification of physicochemical assays, current regulations, the development and reproducibility of clinical trials, as well as, the revolution of omics technologies and state-of-the-art integration and analysis approaches.

查看原文本刊更多论文

精准医学时代的转化生物标志物。

在本章中，我们将讨论临床生物标志物发展的过去、现在和未来。我们探索新技术的出现，为理解健康、医学和疾病铺平道路。这篇综述包括理化分析的鉴定、现行法规、临床试验的发展和可重复性，以及组学技术的革命和最先进的集成和分析方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Advances in Clinical Chemistry 医学-医学实验技术

CiteScore

10.60

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Advances in Clinical Chemistry volumes contain material by leading experts in academia and clinical laboratory science. The reviews cover a wide variety of clinical chemistry disciplines including clinical biomarker exploration, cutting edge microarray technology, proteomics and genomics. It is an indispensable resource and practical guide for practitioners of clinical chemistry, molecular diagnostics, pathology, and clinical laboratory sciences in general.