Bariatric surgery in a patient with cystinuria.

Clinical Nephrology. Case Studies Pub Date : 2021-05-07 eCollection Date: 2021-01-01 DOI:10.5414/CNCS110496
Melissa R Nemati, Peter C Harris, Andrea G Cogal, David S Goldfarb
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Abstract

We recently encountered concern about the safety of bariatric surgery for a patient with cystinuria. Bariatric surgery procedures include those that cause malabsorption, like the Roux-en-Y gastric bypass procedure, and restrictive operations, such as the sleeve gastrectomy. These procedures produce beneficial effects on health and life expectancy, though whether kidney stones are prevented, as well as promoted, is not established. Although the importance of body weight to metabolic stone activity in patients with cystinuria is not established, the patient's physicians were concerned about whether any bariatric surgery procedure would affect her ability to drink sufficient quantities of water in order to reduce stone activity. Here we report the experience of a genetically defined patient with cystinuria who underwent a gastric sleeve procedure. In the months after the procedure, she lost 45 kg, though with time she regained 23 kg of that loss. She was able to maintain a urine volume of 4.0 L per day and has had no stone recurrence.

膀胱尿症患者的减肥手术。
我们最近遇到了对患有胱氨酸尿症患者的减肥手术安全性的关注。减肥手术包括那些引起吸收不良的手术,如Roux-en-Y胃旁路手术,以及限制性手术,如袖式胃切除术。这些手术对健康和预期寿命产生了有益的影响,尽管是否可以预防或促进肾结石,还没有确定。虽然体重对胱氨酸尿症患者代谢结石活动的重要性尚未确定,但该患者的医生担心任何减肥手术是否会影响其饮用足量水以减少结石活动的能力。在这里,我们报告的经验,遗传定义的病人与胱氨酸尿谁接受了胃袖手术。在手术后的几个月里,她减掉了45公斤,但随着时间的推移,她又减掉了23公斤。她能够维持每天4.0升的尿量,并且没有结石复发。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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