Molecular Epidemiology and Phylogeny of Crimean-Congo Haemorrhagic Fever (CCHF) Virus of Ixodid Ticks in Khorasan Razavi Province of Iran.

IF 0.6 4区医学 Q4 PARASITOLOGY

Journal of Arthropod-Borne Diseases Pub Date : 2020-12-31 eCollection Date: 2020-12-01 DOI:10.18502/jad.v14i4.5277

Hossein Maghsood, Sedigheh Nabian, Parviz Shayan, Tahmineh Jalali, Meysam Saboor Darbandi, Mohammad Mehdi Ranjbar

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引用次数: 1

Abstract

Background: Crimean-Congo hemorrhagic fever (CCHF) is a fatal disease caused by Nairovirus classified within the Bunyaviridae family. The virus is transmitted to humans through the bites of infected ticks or direct contact with viremic animals or humans. The current study aimed to detect the virus genome in ticks from Khorasan Razavi Province.

Methods: One hundred hard ticks were collected randomly from 100 sheep in four different areas of the province. Collected ticks were kept alive and identified. All the ticks were analyzed for the presence of CCHF virus genome using reverse transcriptase polymerase chain reactions (RT-PCR).

Results: The identified ticks were belonging to Hyalomma marginatum (16% female and 6% male), Rhipicephalus turanicus (52% female and 25% male), and Dermacentor raskemensis (1%). The CCHF virus genome was found in Hyalomma marginatum (5% male from Taibad and Sabzevar region and 1% female from Taibad). Genetic analysis of the virus genome isolated from two regions (Sabzevar and Taibad) showed 100% identity.

Conclusion: This study indicated that CCHF should be regarded as a risk-borne infection in this province. Therefore, special health management is needed to control this disease.

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伊朗呼罗珊-拉扎维省蜱类克里米亚-刚果出血热病毒的分子流行病学和系统发育

背景:克里米亚-刚果出血热(CCHF)是一种由布尼亚病毒科纳罗病毒引起的致命疾病。该病毒通过受感染蜱虫的叮咬或直接接触带病毒的动物或人类传播给人类。目前的研究旨在检测呼罗珊拉扎维省蜱的病毒基因组。方法:在全省4个不同地区随机采集100只羊硬蜱100只。收集到的蜱虫保持存活并进行鉴定。采用逆转录聚合酶链式反应(RT-PCR)分析所有蜱是否存在CCHF病毒基因组。结果:鉴定的蜱属分别为边缘透明蝇(雌性占16%，雄性占6%)、图兰头蜱(雌性占52%，雄性占25%)和拉斯革蜱(1%)。在边缘透明瘤中发现了CCHF病毒基因组(5%来自Taibad和Sabzevar地区的男性，1%来自Taibad的女性)。从两个地区(Sabzevar和Taibad)分离的病毒基因组的遗传分析显示100%同源。结论:我省应将CCHF视为一种危险传播感染。因此，需要特殊的卫生管理来控制该病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Arthropod-Borne Diseases PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-PARASITOLOGY

CiteScore

2.00

自引率

11.10%

发文量

审稿时长

8 weeks

期刊介绍： The journal publishes original research paper, short communication, scientific note, case report, letter to the editor, and review article in English. The scope of papers comprises all aspects of arthropod borne diseases including: ● Systematics ● Vector ecology ● Epidemiology ● Immunology ● Parasitology ● Molecular biology ● Genetics ● Population dynamics ● Toxicology ● Vector control ● Diagnosis and treatment and other related subjects.