Non-Healing Burn Wound Treatment With A Sterile Silicone Gel.

Q3 Medicine
Annals of burns and fire disasters Pub Date : 2021-03-31
E Lucattelli, F Cipriani, C Pascone, A Di Lonardo
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引用次数: 0

Abstract

Treatment of burn wounds can be complicated due to fluid and electrolyte loss and the increased chance of infectious complications. Silicone-based products have become increasingly used for non-healing wound treatment, but no study has specifically addressed its potential on burn patients. The purpose of this study was to compare the use of sterile silicone gel with conventional medication in improving the healing of burn wounds. Between November 2019 and March 2020, 12 patients with mid-deep and deep burn wounds were included in the present study (average TBSA approximately 29%, range 13-51%). Patient average age was 49 years (range 29-67 years), 7 were male. In each patient two clinically similar areas were identified and treated every 48 hours with topical application of silicone gel in the form of Stratamed® (Group 1) and conventional medication (Group 2). All the cases healed without requiring skin grafting. No secondary wound infection nor allergic reactions were found. The mean days from commencing the treatment to 95% re-epithelialization in Groups 1 and 2 were 5.4 and 12.5, respectively. Culture samples were negative for common pathogens. Silicone gel has shown to be particularly effective in speeding up the re-epithelialization process. The protective film formed by the silicone helps to reduce possible infectious complications. Finally, silicone gel is easy to apply and associated with greater pain control during medication.

用无菌硅胶治疗不愈合的烧伤伤口。
由于液体和电解质的流失以及感染并发症的机会增加,烧伤创面的治疗可能会很复杂。硅基产品越来越多地用于不愈合的伤口治疗,但没有研究专门针对其在烧伤患者中的潜力。本研究的目的是比较使用无菌硅胶与常规药物在改善烧伤创面愈合方面的效果。2019年11月至2020年3月,本研究纳入了12例中深部和深部烧伤创面患者(平均TBSA约29%,范围13-51%)。患者平均年龄49岁(29 ~ 67岁),男性7例。在每位患者中,确定两个临床相似的区域,并每48小时局部应用Stratamed®形式的硅凝胶(组1)和常规药物(组2)进行治疗。所有病例均愈合,无需植皮。无继发性伤口感染及过敏反应。1组和2组从开始治疗到95%再上皮化的平均时间分别为5.4和12.5天。培养样品中常见病原菌均为阴性。硅凝胶已被证明在加速再上皮化过程中特别有效。硅胶形成的保护膜有助于减少可能的感染并发症。最后,硅胶易于应用,并且在服药期间能更好地控制疼痛。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Annals of burns and fire disasters
Annals of burns and fire disasters Nursing-Emergency Nursing
CiteScore
1.20
自引率
0.00%
发文量
0
期刊介绍: "Annals of Burns and Fire Disasters" is the official publication of the Euro-Mediterranean Council for Burns and Fire Disasters (MBC) and the European Burns Association (EBA). It is a peer-reviewed journal directed to an audience of medical as well as paramedical personnel involved in the management of burn injuries. The journal publishes original articles in the form of clinical and basic research, scientific advances. It publishes also selected abstracts from international journals.
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