A stochastic compartmental model to simulate the Covid-19 epidemic spread on a simple network.

IF 1.5 4区 生物学 Q4 Agricultural and Biological Sciences
Armando Bazzani, Enrico Lunedei, Sandro Rambaldi
{"title":"A stochastic compartmental model to simulate the Covid-19 epidemic spread on a simple network.","authors":"Armando Bazzani,&nbsp;Enrico Lunedei,&nbsp;Sandro Rambaldi","doi":"10.19272/202011402004","DOIUrl":null,"url":null,"abstract":"<p><p>The recent Covid-19 epidemic has pointed out the inadequacy of the plans applied by industrial countries to limit the epidemic spread and frailty of the global economy to cope with a pandemic. Many countries were forced to a global lockdown with a great socio-economic impact. In Italy, one of the problems was the complex mobility network structure of the Northern regions that made ineffective the attempts to isolate the initial hotspots. In the paper we study a simple model that simulates the epidemic spread on a community network that may exchange population according to a daily mobility rate. In each community the epidemic evolution is provided by a stochastic compartmental model whose parameters are tuned to reproduce the Covid-19 evolution observed in Italy before the global lockdown policies. We initially study the delay in the epidemic spread due to the finite local mobility by proposing a power law relation for the increasing of the infection peak time in each node and the network distance from the initial node where the epidemic starts. We consider two scenarios to study the effectiveness of local lockdown policies: the presence of two clusters weakly connected by the mobility or a homogeneous chain of communities that exchange the population at a fixed rate. In both cases we show the existence of a threshold effect, in a probabilistic sense, for the effectiveness of lockdown policies as a function of the delay time at which such policies are applied, or of the network distance from the outbreak node.</p>","PeriodicalId":54453,"journal":{"name":"Theoretical Biology Forum","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Theoretical Biology Forum","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.19272/202011402004","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Agricultural and Biological Sciences","Score":null,"Total":0}
引用次数: 1

Abstract

The recent Covid-19 epidemic has pointed out the inadequacy of the plans applied by industrial countries to limit the epidemic spread and frailty of the global economy to cope with a pandemic. Many countries were forced to a global lockdown with a great socio-economic impact. In Italy, one of the problems was the complex mobility network structure of the Northern regions that made ineffective the attempts to isolate the initial hotspots. In the paper we study a simple model that simulates the epidemic spread on a community network that may exchange population according to a daily mobility rate. In each community the epidemic evolution is provided by a stochastic compartmental model whose parameters are tuned to reproduce the Covid-19 evolution observed in Italy before the global lockdown policies. We initially study the delay in the epidemic spread due to the finite local mobility by proposing a power law relation for the increasing of the infection peak time in each node and the network distance from the initial node where the epidemic starts. We consider two scenarios to study the effectiveness of local lockdown policies: the presence of two clusters weakly connected by the mobility or a homogeneous chain of communities that exchange the population at a fixed rate. In both cases we show the existence of a threshold effect, in a probabilistic sense, for the effectiveness of lockdown policies as a function of the delay time at which such policies are applied, or of the network distance from the outbreak node.

一个模拟Covid-19流行病在简单网络上传播的随机区室模型。
最近的新冠肺炎疫情表明,发达国家限制疫情传播的计划存在不足,全球经济应对大流行的能力也很薄弱。许多国家被迫实施全球封锁,造成巨大的社会经济影响。在意大利,问题之一是北部地区复杂的交通网络结构,使得隔离最初热点的尝试无效。在本文中,我们研究了一个简单的模型,该模型模拟了流行病在一个社区网络上的传播,该社区网络可以根据每日流动率交换人口。在每个社区,流行病的演变由一个随机区隔模型提供,该模型的参数经过调整,以重现在全球封锁政策之前在意大利观察到的Covid-19演变。通过建立各节点感染高峰时间与网络距离的幂律关系,初步研究了由于局部流动性有限导致的传染病传播延迟问题。我们考虑了两种情况来研究地方封锁政策的有效性:存在两个由流动性弱连接的集群,或者存在以固定速率交换人口的同质社区链。在这两种情况下,我们在概率意义上表明,对于应用此类策略的延迟时间或与爆发节点的网络距离有关的锁定策略有效性,存在阈值效应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Theoretical Biology Forum
Theoretical Biology Forum 生物-生物学
CiteScore
0.70
自引率
0.00%
发文量
0
审稿时长
>12 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信