Medicines Availability among Hypertensive Patients in Primary Health Care Facilities in a Rural Province in South Africa: Findings and Implications.

IF 0.8 Q4 PHARMACOLOGY & PHARMACY
Journal of Research in Pharmacy Practice Pub Date : 2021-01-11 eCollection Date: 2020-10-01 DOI:10.4103/jrpp.JRPP_20_49
Enos M Rampamba, Johanna C Meyer, Elvera Helberg, Brian Godman
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引用次数: 3

Abstract

Objective: Controlling blood pressure (BP) in hypertensive patients is a challenge, with the lack of antihypertensive medicines negatively impacting on BP control. Consequently, we assessed the availability of prescribed antihypertensives among patients with chronic hypertension attending primary health care (PHC) facilities in a rural province of South Africa and explored any association between medicines availability, the number of prescribed antihypertensive medicines and BP control.

Methods: Secondary data that included patients' demographics, BP, and data on medicines availability of the intervention group from a 3 months' operational study conducted in rural PHC facilities in South Africa were analyzed. The association between medicines availability, the number of antihypertensive medicines, and BP control was explored.

Findings: Fifty-five African patients (89.1% females) with a mean age of 61.3 years were included. Two-thirds (67.2%) received all their medicines during their monthly visits, 25.5% received some, and for 7.3%, there was no record of whether medicines were dispensed or not. Patients with controlled BP (60.0%) were more likely to have been prescribed only one antihypertensive medicine compared to patients with uncontrolled BP (20.7%) (P = 0.017; odds ratio: 5.75; 95% confidence interval: 1.46, 22.61).

Conclusion: It is concerning that one-third of patients went home without all of their antihypertensive medicines from PHC facilities in this Province of South Africa where there is evidence of use of herbal medicines and uncontrolled BP contributing to high morbidity and mortality from cardiovascular diseases. Additional studies are needed to fully explore the association between medicines availability, their use, and BP control among patients.

南非一个农村省初级卫生保健机构中高血压患者的药物可得性:研究结果和意义
目的:控制高血压患者的血压是一个挑战,缺乏降压药会对血压控制产生负面影响。因此,我们评估了南非一个农村省份初级卫生保健(PHC)机构的慢性高血压患者处方抗高血压药物的可获得性,并探讨了药物可获得性、处方抗高血压药物数量和血压控制之间的关系。方法:从南非农村初级保健机构进行的为期3个月的业务研究中,分析了包括患者人口统计学、血压和干预组药物可用性数据在内的次要数据。探讨药物可及性、降压药数量与血压控制之间的关系。结果:55例非洲患者(89.1%为女性),平均年龄61.3岁。三分之二(67.2%)的人在每月就诊时获得了全部药品,25.5%的人获得了部分药品,7.3%的人没有是否配药的记录。血压控制的患者(60.0%)比血压不控制的患者(20.7%)更有可能只开过一种降压药(P = 0.017;优势比:5.75;95%置信区间:1.46,22.61)。结论:令人担忧的是,在南非的这个省,有三分之一的患者回家时没有服用所有的抗高血压药物,有证据表明使用草药和不受控制的血压导致心血管疾病的高发病率和死亡率。需要进一步的研究来充分探索药物的可获得性、使用和患者血压控制之间的关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Research in Pharmacy Practice
Journal of Research in Pharmacy Practice PHARMACOLOGY & PHARMACY-
自引率
0.00%
发文量
8
审稿时长
21 weeks
期刊介绍: The main focus of the journal will be on evidence-based drug-related medical researches (with clinical pharmacists’ intervention or documentation), particularly in the Eastern Mediterranean region. However, a wide range of closely related issues will be also covered. These will include clinical studies in the field of pharmaceutical care, reporting adverse drug reactions and human medical toxicology, pharmaco-epidemiology and toxico-epidemiology (poisoning epidemiology), social aspects of pharmacy practice, pharmacy education and economic evaluations of treatment protocols (e.g. cost-effectiveness studies). Local reports of medication utilization studies at hospital or pharmacy levels will only be considered for peer-review process only if they have a new and useful message for the international pharmacy practice professionals and readers.
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