{"title":"Long-term transmission dynamics of tick-borne diseases involving seasonal variation and co-feeding transmission.","authors":"Kyeongah Nah, Jianhong Wu","doi":"10.1080/17513758.2021.1919322","DOIUrl":null,"url":null,"abstract":"<p><p>Co-feeding is a mode of pathogen transmission for a wide range of tick-borne diseases where susceptible ticks can acquire infection from co-feeding with infected ticks on the same hosts. The significance of this transmission pathway is determined by the co-occurrence of ticks at different stages in the same season. Taking this into account, we formulate a system of differential equations with tick population dynamics and pathogen transmission dynamics highly regulated by the seasonal temperature variations. We examine the global dynamics of the model systems, and show that the two important ecological and epidemiological basic reproduction numbers can be used to fully characterize the long-term dynamics, and we link these two important threshold values to efficacy of co-feeding transmission.</p>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/17513758.2021.1919322","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1080/17513758.2021.1919322","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 3
Abstract
Co-feeding is a mode of pathogen transmission for a wide range of tick-borne diseases where susceptible ticks can acquire infection from co-feeding with infected ticks on the same hosts. The significance of this transmission pathway is determined by the co-occurrence of ticks at different stages in the same season. Taking this into account, we formulate a system of differential equations with tick population dynamics and pathogen transmission dynamics highly regulated by the seasonal temperature variations. We examine the global dynamics of the model systems, and show that the two important ecological and epidemiological basic reproduction numbers can be used to fully characterize the long-term dynamics, and we link these two important threshold values to efficacy of co-feeding transmission.
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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