The role of inflammation biomarkers in differential diagnosis of pelvic tumours of ovarian origin: a single-centre observational study.

IF 2.9 Q2 ONCOLOGY

Wspolczesna Onkologia-Contemporary Oncology Pub Date : 2021-01-01 Epub Date: 2021-04-15 DOI:10.5114/wo.2021.105072

Victoria Psomiadou, Anastasia Prodromidou, Elpis Galati, Ioannis D Kostakis, Athanasios Maliaros, Ioannis Mamais, Nikolaos Blontzos, Fotios Lefkopoulos, Christos Iavazzo, George Vorgias

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引用次数: 2

Abstract

Aim of the study: Our aim was to analyse the feasibility of white blood cell and platelet counts along with their ratios as a prognostic factor in patients who underwent surgery for ovarian mass.

Material and methods: We retrospectively studied the patients admitted in the Department of Gynaecology due to adnexal mass. The potential association of the neutrophil-to-lymphocyte-ratio (NLR), neutrophil-to-monocyte (NMR), platelet-to-lymphocyte (PLR), lymphocyte-to-monocyte (LMR), monocyte-to-platelet, and malignancy was evaluated.

Results: Patients with malignant tumours were found with significantly higher ratios of NLR (p < 0.001) and PLR (p < 0.001) and lower LMR ratio (p < 0.001) compared to those with benign tumours. Furthermore, higher lymphocyte count (p = 0.04) and platelet count (p = 0.004) were found in cancer patients when compared with borderline tumours. No significant variations were detected regarding white blood cell count (p = 0.238), NMR ratio (p = 0.28), platelet-to-neutrophil ratio (p = 0.12), and platelet-to-monocyte ratio (p = 0.34).

Conclusions: Inflammation biomarker ratios can easily and inexpensive assist in distinguishing malignant ovarian tumours from benign ones.

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炎症生物标志物在卵巢源性盆腔肿瘤鉴别诊断中的作用:一项单中心观察研究。

研究目的:我们的目的是分析白细胞和血小板计数及其比率作为卵巢肿块手术患者预后因素的可行性。材料和方法:我们回顾性研究了因附件肿块入院的妇科患者。评估中性粒细胞与淋巴细胞比率(NLR)、中性粒细胞与单核细胞比率(NMR)、血小板与淋巴细胞比率(PLR)、淋巴细胞与单核细胞比率(LMR)、单核细胞与血小板比率和恶性肿瘤之间的潜在关联。结果:恶性肿瘤患者NLR比(p < 0.001)、PLR比(p < 0.001)显著高于良性肿瘤患者，LMR比(p < 0.001)显著低于良性肿瘤患者。此外，与交界性肿瘤患者相比，肿瘤患者淋巴细胞计数(p = 0.04)和血小板计数(p = 0.004)较高。白细胞计数(p = 0.238)、核磁共振比(p = 0.28)、血小板与中性粒细胞比(p = 0.12)和血小板与单核细胞比(p = 0.34)均未发现显著差异。结论:炎症标志物比值可以方便、廉价地帮助鉴别卵巢恶性肿瘤和良性肿瘤。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Wspolczesna Onkologia-Contemporary Oncology 医学-肿瘤学

CiteScore

3.10

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： Contemporary Oncology is a journal aimed at oncologists, oncological surgeons, hematologists, radiologists, pathologists, radiotherapists, palliative care specialists, psychologists, nutritionists, and representatives of any other professions, whose interests are related to cancer. Manuscripts devoted to basic research in the field of oncology are also welcomed.