The Glucose-Lowering Effects of Coconut Oil: A Case Report and Review of the Literature.

IF 0.9 Q4 ENDOCRINOLOGY & METABOLISM
Case Reports in Endocrinology Pub Date : 2020-12-27 eCollection Date: 2020-01-01 DOI:10.1155/2020/8841781
Samar Malaeb, Christopher Spoke
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引用次数: 11

Abstract

Background: Coconut oil, a saturated fat comprised mostly of the medium-chain fatty acid, lauric acid, has become increasingly popular over the past few decades due to its touted anti-inflammatory, metabolic, and lipid-lowering properties. There have been many studies with mixed results evaluating the effects of coconut oil consumption on lipid metabolism and cardiometabolic risk. However, the effects on glucose metabolism are less clear. There are few trials on the effects of coconut oil on glucose homeostasis but no case reports prior to the current one.

Case: We present a case of a 66-year-old man with a history of type 2 diabetes managed with insulin who developed recurrent hypoglycemia and required reduction in insulin therapy quickly after consuming coconut oil supplementation.

Conclusion: This is the first known case report of coconut oil supplementation in a diabetic patient on insulin resulting in hypoglycemia. Review of the literature shows that coconut oil supplementation can have a favorable effect on glycemic control, possibly through phenolic compounds mediating anti-inflammatory effects. This effect is inconsistent throughout the studies reviewed, likely due to variations in types of coconut oil supplementation and scarcity of trials. Further research is required both in animal models and in humans before coconut oil intake is widely advised and popularized. This is especially true in patients with diabetes, who are at increased risk of cardiovascular disease, and in whom reduction in saturated fat intake is advised.

椰子油的降血糖作用:1例报告及文献复习。
背景:椰子油是一种饱和脂肪,主要由中链脂肪酸月桂酸组成,由于其抗炎、代谢和降脂的特性,在过去的几十年里越来越受欢迎。关于椰子油摄入对脂质代谢和心脏代谢风险的影响,已有许多研究得出了不同的结果。然而,对葡萄糖代谢的影响尚不清楚。很少有关于椰子油对葡萄糖稳态影响的试验,但在此之前没有病例报告。病例:我们报告了一位66岁的男性患者,他有2型糖尿病史,使用胰岛素治疗,在服用椰子油补充剂后,他出现了复发性低血糖,需要迅速减少胰岛素治疗。结论:这是已知的第一例补充椰子油的糖尿病患者胰岛素导致低血糖。文献综述表明,补充椰子油可能通过酚类化合物介导抗炎作用,对血糖控制有良好的影响。这种影响在所有研究中都是不一致的,可能是由于椰子油补充类型的变化和试验的缺乏。在椰子油的摄入被广泛建议和推广之前,还需要在动物模型和人类身上进行进一步的研究。糖尿病患者尤其如此,他们患心血管疾病的风险增加,建议减少饱和脂肪的摄入。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Case Reports in Endocrinology
Case Reports in Endocrinology ENDOCRINOLOGY & METABOLISM-
CiteScore
2.10
自引率
0.00%
发文量
45
审稿时长
13 weeks
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