Severity of Mitral Regurgitation before and after Kidney Transplantation.

IF 0.3 Q4 TRANSPLANTATION
G Pourmand, S Karbalai Saleh, A Mehrsai, S Gooran, M R Khajavi, E Razeghi, M Rahbar, M Pourhossein, S Dehghani
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引用次数: 0

Abstract

Background: Perivalvular and valve involvement are prevalent in patients with end-stage renal disease (ESRD), especially in younger patients compared with normal population. Kidney transplantation improves the prognosis of these patients. Patients with cardiac valvular disease is also be improved following kidney transplantation.

Objective: To evaluate the impact of renal transplantation on the severity of mitral regurgitation (MR).

Methods: We studied 95 kidney transplantation candidates in Sina Hospital. The patients underwent echocardiography preoperatively and at the 3rd, 6th, and 12th months post-operatively.

Results: Pre-operatively, the average MR fraction was 30%; MR volume 30 mL/beat; mitral valve mean gradient 1.8 mm Hg; mitral valve area 4.6 cm2; and mitral annular size 3 cm. No significant difference was observed among the measurements made at the 3rd, 6th, and 12th months post-operatively.

Conclusion: There was no significant association between the variables measured pre- and post-operatively. The reason might be the fact that patients with ESRD in Iran do not have to expect long transplant waiting lists and dialysis cannot affect their heart adversely.

肾移植前后二尖瓣反流的严重程度。
背景:与正常人群相比,终末期肾病(ESRD)患者瓣膜周围和瓣膜受累很普遍,尤其是年轻患者。肾移植可改善这些患者的预后。心脏瓣膜疾病患者在肾移植后也得到改善。目的:探讨肾移植对二尖瓣反流(MR)严重程度的影响。方法对新浪医院95例肾移植候选者进行研究。患者术前及术后第3、6、12个月行超声心动图检查。结果:术前平均MR分数为30%;MR体积30 mL/次;二尖瓣平均梯度1.8 mm Hg;二尖瓣面积4.6 cm2;二尖瓣环大小为3厘米。术后第3、6、12个月的测量结果无显著差异。结论:术前、术后各项指标无显著相关性。原因可能是伊朗的ESRD患者不必期待长时间的移植等待名单,并且透析不会对心脏产生不利影响。
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来源期刊
CiteScore
1.60
自引率
0.00%
发文量
0
审稿时长
12 weeks
期刊介绍: The International Journal of Organ Transplantation Medicine (IJOTM) is a quarterly peer-reviewed English-language journal that publishes high-quality basic sciences and clinical research on transplantation. The scope of the journal includes organ and tissue donation, procurement and preservation; surgical techniques, innovations, and novelties in all aspects of transplantation; genomics and immunobiology; immunosuppressive drugs and pharmacology relevant to transplantation; graft survival and prevention of graft dysfunction and failure; clinical trials and population analyses in the field of transplantation; transplant complications; cell and tissue transplantation; infection; post-transplant malignancies; sociological and ethical issues and xenotransplantation.
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