The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties.

IF 1.5 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
JRSM Cardiovascular Disease Pub Date : 2020-11-11 eCollection Date: 2020-01-01 DOI:10.1177/2048004020973094
Hasan Akkaya, Ertuğrul Emre Güntürk
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引用次数: 0

Abstract

Introduction: In this study, we aimed to investigate the relationship between coronary slow flow (CSF) and carotid-femoral pulse wave velocity (CFPWV).

Methods: 78 (27 women, mean age 43.95 ± 7.28) patients with CSF, and 70 (22 women, mean age 44.34 ± 7.08) healthy individuals were included in the study. Arterial stiffness measurement was performed to both groups via CFPWV, which is considered the gold standard. Aortic elastic properties (ASI-β and aortic distensibility) were evaluated in both groups.

Results: The CSF group had significantly higher CFPWV and aortic distensibility values and significantly lower ASI-β values compared to the control group. There was a positive correlation between TIMI frame count (TFC) obtained in all coronary arteries and CFPWV and aortic distensibility, and a negative correlation between TFC and ASI-β. It was determined that CFPWV predicted CSF with 97% specificity and 98% sensitivity at a 7.68 cut-off value (ROC area = 994, p < 0.001). ASI-β was determined to predict CSF with 64% specificity and 47% sensitivity at a 2.98 cut-off value (ROC area = 047, p < 0.001). Aortic distensibility was determined to predict CSF with 76% specificity and 79% sensitivity at a 3.94 cut-off value (ROC area = 706, p < 0.001).

Conclusion: Arterial stiffness increases in CSF patients, suggesting that CSF is a systemic pathology rather than a local disease and that a systemic cause such as atherosclerosis plays a role in etiology.

Abstract Image

Abstract Image

Abstract Image

冠状动脉慢血流现象与颈动脉股脉波速度及主动脉弹性特性的关系。
在本研究中,我们旨在探讨冠状动脉慢血流(CSF)与颈-股脉波速度(CFPWV)的关系。方法:78例脑脊液患者(女性27例,平均年龄43.95±7.28岁)和70例健康人(女性22例,平均年龄44.34±7.08岁)纳入研究。通过CFPWV对两组进行动脉硬度测量,这被认为是金标准。评估两组患者的主动脉弹性特性(ASI-β和主动脉扩张性)。结果:与对照组相比,CSF组CFPWV和主动脉扩张系数显著升高,ASI-β值显著降低。所有冠状动脉TIMI框架计数(TFC)与CFPWV和主动脉扩张率呈正相关,TFC与ASI-β呈负相关。结果表明,CFPWV预测CSF的特异性为97%,敏感性为98%,临界值为7.68 (ROC area = 994), p结论:脑脊液患者动脉僵硬度增加,提示脑脊液是一种全身性病理而非局部疾病,动脉粥样硬化等全身性病因在病因学中起作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
JRSM Cardiovascular Disease
JRSM Cardiovascular Disease CARDIAC & CARDIOVASCULAR SYSTEMS-
自引率
6.20%
发文量
12
审稿时长
12 weeks
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