The Effect of Single-Dose Bupivacaine on Postoperative Iliac Crest Graft Donor Site Pain.

Nigerian Journal of Surgery Pub Date : 2020-07-01 Epub Date: 2020-07-27 DOI:10.4103/njs.NJS_68_19
Olalere Omoyosola Gbolahan, Babatunde Babasola Osinaike, Adeola Olanike Olusanya, Michael Oluyinka Okunola
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Abstract

Background: Postoperative donor site pain remains a major source of morbidity following iliac crest bone graft harvesting (ICBGH).

Aim: The aim of this study was to investigate the effect of single-dose infiltration of bupivacaine on donor site pain following ICBGH.

Subjects and methods: This study was a double-blind randomized controlled trial of 30 adult individuals that required an ICBG as part of the treatment for mandibular reconstruction. Individuals were divided into two groups, to receive a single-dose subcutaneous infiltration of either 0.25% bupivacaine or 0.9% normal saline at the iliac crest graft incision site following ICBGH. Length of incision at the ICBGH site, dimensions of harvested graft, time taken for the iliac crest harvest surgery, total daily dose of postoperative analgesics, pain from the ICBGH site as well as gait disturbance were recorded. Data were analyzed using SPSS version 17.0, and P < 0.05 was considered statistically significant.

Results: There was a progressive decrease in pain score from the 1st to the 4th postoperative day, with no significant difference between the two groups. There was no statistical difference between the two groups in terms of dynamic median pain score at the early postoperative period as well as at the 4th and 12th week postoperative period. The analgesic consumption between the two groups also did not show any significant difference.

Conclusion: Local injection of single dose of 0.25% bupivacaine did not offer additional benefit in the management of postoperative iliac crest donor site pain following ICBGH.

Abstract Image

单剂量布比卡因对髂骨移植术后供区疼痛的影响。
背景:术后供区疼痛仍然是髂嵴骨移植(ICBGH)术后发病的主要原因。目的:本研究旨在探讨单剂量布比卡因对ICBGH术后供区疼痛的影响。对象和方法:本研究是一项双盲随机对照试验,30名成年人需要ICBG作为下颌重建治疗的一部分。个体被分为两组,在ICBGH后接受0.25%布比卡因或0.9%生理盐水在髂骨移植切口处单剂量皮下浸润。记录ICBGH部位的切口长度、移植骨的尺寸、髂骨切除手术所需的时间、术后镇痛药的每日总剂量、ICBGH部位的疼痛以及步态障碍。数据采用SPSS 17.0版本进行分析,P < 0.05为差异有统计学意义。结果:术后第1天至第4天疼痛评分逐渐降低,两组间差异无统计学意义。两组患者术后早期及术后第4周、第12周动态中位疼痛评分比较,差异均无统计学意义。两组镇痛药用量也无显著差异。结论:局部注射单剂量0.25%布比卡因对ICBGH术后髂嵴供区疼痛的治疗没有额外的益处。
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