Ru(ii)-catalyzed C–H alkynylation of ferrocenes with bromoalkynes directed by carboxamide groups†

Abstract

An efficient synthesis of ferrocene derivatives via Ru(ii)-catalyzed direct selective C–H mono-alkynylation with easily accessible bromoalkyne compounds under the influence of weakly coordinating amide groups has been presented. This protocol provides an approach for accessing various ferrocene derivatives with easily transformed alkynes using carboxamides, giving alkynylated ferrocenes in up to 89% yield.