Estimation of skin impedance models with experimental data and a proposed model for human skin impedance

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Dhruba Jyoti Bora, Rajdeep Dasgupta
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引用次数: 11

Abstract

The skin is a complex biological tissue whose impedance varies with frequency. The properties and structure of skin changes with the location on the body, age, geographical location and other factors. Considering these factors, skin impedance analysis is a sophisticated data analysis. However, despite all these variations, various researchers have always worked to develop an equivalent electrical model of the skin. The two most important categories of electrical models are RC-based model and CPE-based model which focus on the physiological stratification and biological properties of skin, respectively. In this work, experimental skin impedance data is acquired from ten sites on the body to find the fitting model. It is observed that a hybrid of fractional-order CPE-based model and higher-order RC layered-based model can provide the best fitting electrical model of skin. A new model is developed with this hybrid orders. Genetic algorithm is used for the extraction of parameter components. Least error of fitting has been observed for the proposed model as compared with the other models. This model can be used in correlating many skin problems and in the development of diagnostic tools. It will offer an additional supportive tool in-vitro to the medical specialist.

Abstract Image

用实验数据估计皮肤阻抗模型,并提出一种人体皮肤阻抗模型
皮肤是一种复杂的生物组织,其阻抗随频率而变化。皮肤的性质和结构随着身体的位置、年龄、地理位置等因素而变化。考虑到这些因素,皮肤阻抗分析是一项复杂的数据分析。然而,尽管有这些变化,不同的研究人员一直在努力开发一个等效的皮肤电模型。两类最重要的电模型是基于rc的模型和基于cpe的模型,它们分别关注皮肤的生理分层和生物学特性。在这项工作中,我们从身体的十个部位获取皮肤阻抗的实验数据来寻找拟合模型。结果表明,分数阶cpe模型和高阶RC分层模型的混合模型可以提供最适合皮肤的电模型。利用这种混合订单开发了一种新的模型。采用遗传算法对参数分量进行提取。与其他模型相比,该模型的拟合误差最小。该模型可用于许多皮肤问题的关联和诊断工具的开发。它将为医学专家提供额外的体外辅助工具。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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