[Tetanus Observation Over a 12-Month Period in Conakry, Guinea].

Q4 Medicine

Bulletin de la Societe de pathologie exotique Pub Date : 2019-01-01 DOI:10.3166/bspe-2020-0105

M Oury Safiatou Diallo, A Diaré, F Amara Traoré, F Bangaly Sako, M Saliou Sow, A Oumou Sylla, I Bah, K Sylla, M Cisse

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Abstract

The objective of this study was to determine the factors associated with death in patients hospitalized for tetanus. This study collected prospectively over a twelve (12) month period, the epidemiological, clinical and evolutionary data, and proceeded to an analysis of the factors associated with the death of hospitalized patients. We collected 32 patients with tetanus, or 5% of the total number of hospitalized patients. The average age was 36 ± 14 years. The sex ratio was 15 (30/2). The iatrogenic entrance door was found in 5 (15%) patients. Respiratory complications were the most frequent, ie 9 cases (28%). The most commonly used treatment regimen (28 cases, 88%) was the combination of metronidazole, diazepam, and anti-tetanus serum with an average hospital stay of 23 days. A Dakar prognostic score greater than or equal to 3, the presence of complications and a hospital stay of less than or equal to 7 days were the main factors associated with the death. Tetanus remains common in Guinea with a high lethality rate. Improving immunization coverage is imperative.

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[几内亚科纳克里12个月的破伤风观察]。

本研究的目的是确定破伤风住院患者死亡的相关因素。本研究前瞻性地收集了为期12个月的流行病学、临床和进化数据，并分析了与住院患者死亡相关的因素。我们收集了32例破伤风患者，占住院患者总数的5%。平均年龄36±14岁。性别比为15(30/2)。医源性入口门5例(15%)。呼吸道并发症最常见，共9例(28%)。最常用的治疗方案是甲硝唑、地西泮和抗破伤风血清联合用药(28例，88%)，平均住院时间为23天。达喀尔预后评分大于或等于3分、出现并发症和住院时间小于或等于7天是与死亡相关的主要因素。破伤风在几内亚仍然很常见，死亡率很高。提高免疫覆盖率势在必行。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Bulletin de la Societe de pathologie exotique Medicine-Medicine (all)

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期刊介绍： Le Bulletin de la Société de pathologie exotique et la société savante (SPE) dont il est la vitrine ont été créés en 1908 par Alphonse Laveran. Destiné, dans un premier temps, à servir de support à la publication des travaux des sociétaires présentés en séance sous forme de communication ou de mémoire, ce périodique est devenu, au fil du temps, une revue internationale francophone multidisciplinaire, ouverte à tous les médecins, vétérinaires, anthropologues et chercheurs travaillant dans le domaine de la médecine tropicale humaine et animale et de la santé publique dans les pays en voie de développement.