Taste and Pain Response in Burning Mouth Syndrome With and Without Geographic Tongue.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2020-06-01 DOI:10.11607/ofph.2565

Nan Su, Renee Poon, Cindy Liu, Crystal Dewan, Mark Darling, Miriam Grushka

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引用次数: 8

Abstract

Aims: To assess the effect of geographic tongue (GT) on taste, salivary flow, and pain characteristics in burning mouth syndrome (BMS) to determine whether GT is a contributing factor to BMS and whether BMS and GT represent similar patient populations.

Methods: A retrospective chart study was conducted. Patients with a diagnosis of BMS or BMS/GT were included. Data regarding smell testing, spatial taste-testing, salivary flow, oral pH, and subjective pain rating on a generalized labeled magnitude scale (gLMS) were collected.

Results: No significant differences in age, gender, oral pH, smell, or pain were found between groups. Stimulated and unstimulated salivary flow were significantly lower in BMS/GT. Taste responses to all taste stimuli and to ethanol were significantly lower in BMS, with the exception of sour at the fungiform papillae.

Conclusion: BMS and BMS/GT present with similar clinical pain phenotype and demographics; however, taste was more intact in BMS/GT, suggesting that GT may be a contributing factor in the development of BMS through a mechanism that does not involve taste.

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有无地理舌头灼口综合征的味觉和疼痛反应。

目的:评估地理舌头(GT)对灼口综合征(BMS)的味觉、唾液流和疼痛特征的影响，以确定GT是否是灼口综合征的促成因素，以及BMS和GT是否代表相似的患者群体。方法:采用回顾性图表研究。包括诊断为BMS或BMS/GT的患者。收集了嗅觉测试、空间味觉测试、唾液流量、口腔pH值和广义标记幅度量表(gLMS)主观疼痛评分的数据。结果:两组患者在年龄、性别、口腔pH值、气味、疼痛等方面均无显著差异。BMS/GT组受刺激和未受刺激的唾液流量显著降低。除了真菌状乳头处的酸外，BMS对所有味觉刺激和乙醇的味觉反应都明显较低。结论:BMS和BMS/GT具有相似的临床疼痛表型和统计学特征;然而，味觉在BMS/GT中更为完整，这表明GT可能是通过不涉及味觉的机制促进BMS发展的一个因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.