Occupational allergic contact urticaria to tropomyosin from squid.

Allergologie Select Pub Date : 2020-12-08 eCollection Date: 2020-01-01 DOI:10.5414/ALX02121E
Daniel Wilfinger, Annette Kuehn, Szandra Takacs, Evgenia Galli-Novak, Barbara Machan, Werner Aberer
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引用次数: 1

Abstract

A cook's mate working in an Austrian restaurant reported acutely occurring urticarial skin lesions after processing and cooking squid. The prick-to-prick test with squid showed a ++ positive urticarial reaction. Elevated specific IgE antibody levels to squid, shrimp, and house dust mites as well as to tropomyosin from shrimp and house dust mite could be detected in the ImmunoCAP. By means of immunoblot and ELISA, a reaction to squid extract as well as increased IgE antibody levels to squid and tropomyosin from squid could be detected. The patient was diagnosed with a clinically and occupationally relevant type I allergy to squid with cross-reaction to tropomyosin of other invertebrates and therefore recognized as an occupational disease.

Abstract Image

鱿鱼原肌球蛋白致职业性过敏性接触性荨麻疹。
一名在奥地利餐馆工作的厨师长报告说,在加工和烹饪鱿鱼后出现了急性荨麻疹皮肤病变。鱿鱼刺对刺试验显示++阳性荨麻疹反应。免疫cap检测到鱿鱼、虾和屋尘螨特异性IgE抗体水平升高,虾和屋尘螨原肌球蛋白抗体水平升高。通过免疫印迹和酶联免疫吸附检测,可以检测到小鼠对鱿鱼提取物的反应以及对鱿鱼和鱿鱼原肌球蛋白的IgE抗体水平升高。患者被诊断为与临床和职业相关的鱿鱼I型过敏,并与其他无脊椎动物原肌球蛋白交叉反应,因此被认定为职业病。
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