Demographics of Rhesus Phenotype of Blood Donors in Calabar: A Case Study of University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria.

Q3 Medicine

Advances in Hematology Pub Date : 2020-08-27 eCollection Date: 2020-01-01 DOI:10.1155/2020/2659398

Joyce Ezekiel Etura, Rose A Amaechi, Josephine O Akpotuzor, Henshaw Uchechi Okoroiwu

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引用次数: 3

Abstract

Background: Rhesus antigens have been documented to cause haemolytic disease of the newborn as well as acute and delayed transfusion reactions. This study was performed to evaluate the frequency of rhesus antigens (C, c, D, E, and e) in the studied population.

Method: This study was a cross-sectional study involving 130 prospective blood donors attending University of Calabar Teaching Hospital (UCTH) donor clinic. Donors were grouped for Rh antisera (anti-E, anti-e, anti-C, anti-c, and anti-D) using the standard serologic technique.

Result: The most prevalent Rh antigen was "c" (98.5%), followed by "D" (97.7%), while the least was "C" (30.7%). The most prevalent phenotype was cDe/cDe (R₀R₀).

Conclusion: This work therefore concludes that the most prevalent rhesus antigen and rhesus phenotype was c and cDe/cDe among blood donors in University of Calabar Teaching Hospital.

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卡拉巴尔市献血者恒河猴表型的人口统计学特征:以尼日利亚克罗斯河州卡拉巴尔市卡拉巴尔大学教学医院为例

背景:恒河猴抗原已被证实可引起新生儿溶血性疾病以及急性和延迟性输血反应。本研究旨在评估研究人群中恒河猴抗原(C、C、D、E和E)的频率。方法:本研究是一项横断面研究，涉及130名在卡拉巴大学教学医院(UCTH)献血者诊所就诊的潜在献血者。使用标准血清学技术对献血者进行Rh抗血清(抗e、抗e、抗c、抗c和抗d)分组。结果:Rh抗原中c型最多(98.5%)，D型次之(97.7%)，c型最少(30.7%)。最常见的表型为cDe/cDe (R0R0)。结论:在卡拉巴大学教学医院献血者中，恒河猴抗原和恒河猴表型最常见的是c和cDe/cDe。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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