Influence of isolation measures for patients with mild symptoms on the spread of COVID-19.

IF 5.6
Chaos, solitons, and fractals Pub Date : 2020-10-01 Epub Date: 2020-06-30 DOI:10.1016/j.chaos.2020.110022
Qiuhui Pan, Ting Gao, Mingfeng He
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引用次数: 16

Abstract

During the transmission of COVID-19, the hospital isolation of patients with mild symptoms has been a concern. In this paper, we use a differential equation model to describe the propagation of COVID-19, and discuss the effects of intensity of hospital isolation and moment of taking measures on development of the epidemic. The results show that isolation measures can significantly reduce the epidemic final size and the number of dead, and the greater the intensity of measures, the better, but duration of the epidemic will be prolonged. Whenever isolation measures are taken, the epidemic final size and the number of dead can be reduced. In early stage of the epidemic, taking measures one day later has little impact, but after a certain period, if taking measures one day later, the epidemic final size and the number of dead increase sharply. Taking measures as early as possible makes the maximum number of patients appear later, which is conducive to expanding medical bed resources and reducing the pressure on medical resource demand. As long as possible, high-intensity isolation measures should be taken in time for patients with mild symptoms.

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轻症患者隔离措施对新冠肺炎传播的影响
在COVID-19传播期间,医院对轻度症状患者的隔离一直令人担忧。本文采用微分方程模型描述COVID-19的传播过程,并讨论了医院隔离强度和采取措施的时机对疫情发展的影响。结果表明,隔离措施能显著降低疫情最终规模和死亡人数,且隔离力度越大效果越好,但会延长疫情持续时间。只要采取隔离措施,就可以减少疫情的最终规模和死亡人数。在疫情初期,晚一天采取措施影响不大,但在一定时期后,如果晚一天采取措施,疫情的最终规模和死亡人数会急剧增加。尽早采取措施,最大限度地延迟患者出现,有利于扩大医疗床位资源,减轻医疗资源需求压力。对于症状较轻的患者,应尽可能及时采取高强度隔离措施。
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