{"title":"Pesticide Risk and Recurrent Pregnancy Loss in Females of Subhumid Region of India.","authors":"Akancha Pandey, Shyam Pyari Jaiswar, Nasreen Ghazi Ansari, Sujata Deo, Pushplata Sankhwar, Shriya Pant, Sushil Upadhyay","doi":"10.4103/nmj.NMJ_117_18","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study is to determine the level of pesticides and their role in cases of recurrent pregnancy loss (RPL).</p><p><strong>Materials and methods: </strong>This was designed as a case-control study. Gas chromatography was used to characterize the pesticide level in 70 cases and 70 controls. Case refers to women with RPL, whereas controls refer to women with full-term delivery.</p><p><strong>Results: </strong>A higher level of pesticide, namely beta-hexachlorocyclohexane, malathion, chlorpyrifos, and fenvalerate was found in the case group as compared to control group (<i>P</i> < 0.05).</p><p><strong>Conclusions: </strong>The present study suggests that high exposure of pesticide (organochlorine and organophosphates) may increase the risk of RPL in females of the subhumid region of India.</p>","PeriodicalId":19223,"journal":{"name":"Nigerian Medical Journal : Journal of the Nigeria Medical Association","volume":"61 2","pages":"55-59"},"PeriodicalIF":0.0000,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cb/08/NMJ-61-55.PMC7357805.pdf","citationCount":"9","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nigerian Medical Journal : Journal of the Nigeria Medical Association","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/nmj.NMJ_117_18","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2020/5/7 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 9
Abstract
Objective: The objective of this study is to determine the level of pesticides and their role in cases of recurrent pregnancy loss (RPL).
Materials and methods: This was designed as a case-control study. Gas chromatography was used to characterize the pesticide level in 70 cases and 70 controls. Case refers to women with RPL, whereas controls refer to women with full-term delivery.
Results: A higher level of pesticide, namely beta-hexachlorocyclohexane, malathion, chlorpyrifos, and fenvalerate was found in the case group as compared to control group (P < 0.05).
Conclusions: The present study suggests that high exposure of pesticide (organochlorine and organophosphates) may increase the risk of RPL in females of the subhumid region of India.