The cost-effectiveness of insulin analogs and regular insulin for diabetes control: a case study in Iran.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Mohsen Pakdaman, Raheleh Akbari, Hamid Reza Dehghan, Asra Asgharzadeh, Mahdieh Namayandeh
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Abstract

Purpose: For years, traditional techniques have been used for diabetes treatment. There are two major types of insulin: insulin analogs and regular insulin. Insulin analogs are similar to regular insulin and lead to changes in pharmacokinetic and pharmacodynamic properties. The purpose of the present research was to determine the cost-effectiveness of insulin analogs versus regular insulin for diabetes control in Yazd Diabetes Center in 2017.

Design/methodology/approach: In this descriptive-analytical research, the cost-effectiveness index was used to compare insulin analogs and regular insulin (pen/vial) for treatment of diabetes. Data were analyzed in the TreeAge Software and a decision tree was constructed. A 10% discount rate was used for ICER sensitivity analysis. Cost-effectiveness was examined from a provider's perspective.

Findings: QALY was calculated to be 0.2 for diabetic patients using insulin analogs and 0.05 for those using regular insulin. The average cost was $3.228 for analog users and $1.826 for regular insulin users. An ICER of $0.093506/QALY was obtained. The present findings suggest that insulin analogs are more cost-effective than regular insulin.

Originality/value: This study was conducted using a cost-effectiveness analysis to evaluate insulin analogs versus regular insulin in controlling diabetes. The results of study are helpful to the government to allocate more resources to apply the cost-effective method of the treatment and to protect patients with diabetes from the high cost of treatment.

胰岛素类似物和常规胰岛素用于糖尿病控制的成本效益:伊朗的案例研究。
目的:多年来,传统技术一直用于糖尿病治疗。胰岛素主要有两种:胰岛素类似物和普通胰岛素。胰岛素类似物与常规胰岛素相似,导致药代动力学和药效学性质的变化。本研究的目的是确定2017年亚兹德糖尿病中心胰岛素类似物与常规胰岛素在糖尿病控制方面的成本效益。设计/方法/方法:在这项描述性分析研究中,成本-效果指数用于比较胰岛素类似物和常规胰岛素(笔/瓶)治疗糖尿病。在TreeAge软件中对数据进行分析,构建决策树。采用10%的贴现率进行ICER敏感性分析。从提供者的角度审查了成本效益。结果:计算出使用胰岛素类似物的糖尿病患者的质量aly为0.2,使用常规胰岛素的糖尿病患者的质量aly为0.05。模拟胰岛素使用者的平均费用为3.228美元,普通胰岛素使用者的平均费用为1.826美元。ICER为0.093506美元/QALY。目前的研究结果表明,胰岛素类似物比普通胰岛素更具成本效益。原创性/价值:本研究采用成本效益分析来评估胰岛素类似物与常规胰岛素在控制糖尿病中的作用。研究结果有助于政府分配更多的资源,采用具有成本效益的治疗方法,保护糖尿病患者免于高昂的治疗费用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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